PURPOSE To quantify fundus autofluorescence (qAF) in patients with recessive Stargardt disease (STGD1). METHODS A total of 42 STGD1 patients (ages: 7-52 years) with at least one confirmed disease-associated ABCA4 mutation were studied. Fundus AF images (488-nm excitation) were acquired with a confocal scanning laser ophthalmoscope equipped with an internal fluorescent reference to account for...

Diabetic retinopathy is a micro vascular complication which is characterized by several changes in the retina. Changes occur in the diameter of the blood vessel, microaneurysm, hemorrhage exudates, and the growth of new blood vessels. These changes need to be detected early so that steps for further handling and treatment can be determined. Laser therapy is one of the common therapies for patie...

PURPOSE To evaluate the ophthalmoscopic appearance of the normal optic disc, parapapillary region, and retinal nerve fiber layer in rhesus monkeys. METHODS Color stereo fundus photographs of 17 normal eyes of 17 rhesus monkeys aged between 13 and 23 years were morphometrically evaluated. RESULTS The neuroretinal rim was significantly (P: < 0.008) broadest in the inferior disc region followe...

OBJECTIVES Determine the frequency of and the predictive factors for abnormal ocular fundus findings among emergency department (ED) headache patients. METHODS Cross-sectional study of prospectively enrolled adult patients presenting to our ED with a chief complaint of headache. Ocular fundus photographs were obtained using a nonmydriatic fundus camera that does not require pupillary dilation...

A 57 year old woman was presented to the emergency department with upper abdominal pain and left sided chest discomfort. No cardiac or pulmonary cause could be determined and the patient underwent upper gastrointestinal endoscopy. Inversion of the scope to the fundus and subsequent fluoroscopy revealed a diaphragmatic hernia with a large herniation of the gastric fundus. Immediate laparotomy sh...

We describe the management of a woman aged 52 years with molecularly confirmed Sorsby fundus dystrophy, who presented with acute visual deterioration in her right eye. Fundus examination identified a right macular lesion suggestive of a choroidal neovascular membrane (CNVM). Optical coherence tomography angiography (OCTA) confirmed the presence of a CNVM. She was treated with 2 monthly intravit...

In this paper, a method for automatic detection of microaneurysms in digital eye fundus image is described. To develop an automated diabetic retinopathy screening system, a detection of dark lesions in digital fundus photographs is needed. Microaneurysms are the first clinical sign of diabetic retinopathy and they appear small red dots on retinal fundus images. The number of microaneurysms is u...