• Administration of methylprednisolone (MP) for the treatment of acute spinal cord injury (SCI) is not recommended. Clinicians considering MP therapy should bear in mind that the drug is not Food and Drug Administration (FDA) approved for this application. There is no Class I or Class II medical evidence supporting the clinical benefit of MP in the treatment of acute SCI. Scattered reports of C...

A remotely delivered contraceptive was developed that suppressed estrus and prevented pregnancy in deer with 100-percent efficacy. This contraceptive utilized norgestomet, a potent progestin that is approved by the Food and Drug Administration (FDA) for use in cattle. Although the needle-less norgestomet implant is not FDA approved for use in deer, it is safe for treated animals, humans, and th...

The Food and Drug Administration (FDA or we) is issuing a final rule to establish requirements for shippers, loaders, carriers by motor vehicle and rail vehicle, and receivers engaged in the transportation of food, including food for animals, to use sanitary transportation practices to ensure the safety of the food they transport. This action is part of our larger effort to focus on prevention ...

Patients diagnosed with metastatic soft-tissue sarcoma (STS) have a poor prognosis. Additionally, after failure of first-line therapy, there are relatively few treatment options from which to choose. The novel tubulin-binding drug, eribulin, with a unique mechanism of action from taxanes or vinca alkaloids, has shown clinical activity in several different types of cancers. Eribulin has been app...

For approval of a drug product, the United States Food and Drug Administration (FDA) requires that substantial evidence of the effectiveness and safety of the drug product be provided through the conduct of two adequate, well-controlled clinical trials. To assist the sponsors in preparation of final clinical reports for regulatory submission and review, the FDA and other regulatory agencies and...

After years or detailed study and analysis, the U.S. Food and Drug Administration (FDA) has concluded that meat and milk from clones of cattle, swine (pigs), and goats, and non-cloned offspring is as safe to eat as the food from conventionally bred animals. Researchers have been cloning livestock since 1996 to help improve the quality of herd and the meat and milk from these animals has now bee...

A long time has passed since I last gave chemotherapy, but I have not been immune to the news about the drug shortages in the past few years. Therefore, I wanted to explore what was behind the headlines like “U.S. facing cancer drug shortage: Ariz. doctors rationing supplies; FDA allowing India imports” in the February 22nd Arizona Business News (Alltucker, 2012). You may have been more directl...

Lately, many products with the active ingredient cannabidiol (CBD) have been sold around world. Cannabidiol is an annual herb of cannabis plant that known to no euphoric effects. Another type terpenophenolic compound as cannabinoids also preserved in structure plant. Products containing CBD are offered on market drugs, food supplements or dietary supplements. The US Food and Drug Administration...

•We estimate that the response to genome-targeted therapy increased from 2.73% in 2006 7.04% 2020.•The percentage of patients with cancer United States who responded was modest.•Most increase seen before 2018, and most eligibility after 2018. BackgroundPrior studies have evaluated advanced or metastatic are eligible for respond therapy, but since publication, number Food Drug Administration (FD...