The cerebellum is involved in the update of motor commands during error-dependent learning. Transcranial direct current stimulation (tDCS), a form of noninvasive brain stimulation, has been shown to increase cerebellar excitability and improve learning in motor adaptation tasks. Although cerebellar involvement has been clearly demonstrated in adaptation paradigms, a type of task that heavily re...

Motor skill learning is critical in post-stroke motor recovery, but little is known about its underlying neural substrates. Recently, using a new visuomotor skill learning paradigm involving a speed/accuracy trade-off in healthy individuals we identified three subpopulations based on their behavioral trajectories: fitters (in whom improvement in speed or accuracy coincided with deterioration in...

This study examined the relationship between motor skill competence, and physical activity in 8–9 years-old girls (N=352). Locomotor and object control skill competence was assessed, using the Test of Gross Motor Development-2, and the Physical Activity Questionnaire for Children was used to assess physical activity. Regression analysis revealed that locomotor proficiency accounted for 20% (P...

During sensorimotor skill acquisition, early learning of the required neuromuscular pattern and sensorimotor mappings is followed by an intermediate stage of gradually increasing consistency and efficiency of execution, which gives way, with persistent practice, to the later stages of automatization. It has been suggested that the intermediate stage is distinguished by refinements in the backgr...

Androgenic hormones regulate many aspects of animal social behavior, including the elaborate display routines on which many species rely for advertisement and competition. One way that this might occur is through peripheral effects of androgens, particularly on skeletal muscles that control complex movements and postures of the body and its limbs. However, the specific contribution of periphera...

The purpose of this study was to investigate the potential long-term association of motor skill proficiency at 6 years of age and self-reported physical activity (PA) at age 26. Direct motor performance data were collected in 1991 with a follow-up study occurring in 1996, and then indirect questionnaires (self-report) administered in 2001 and 2011. In 2011, 17 participants who were identified a...

Objectives: This study aimed to compare the combination of CIMT and BIM training with CIMT in Fine Motor Skills of Children with Hemiplegic cerebral palsy. Methods: 24 children with hemiplegic cerebral palsy aged between 60 and 120 months participated in this RCT study. They were randomly assigned into CIMT and BIM training (n=12, four males, eight females mean age±standard deviation=93.58±1...

Motor-skill learning induces changes in synaptic structure and function in the primary motor cortex through the involvement of a long-term potentiation- (LTP-) like mechanism. Although there is evidence that calcium-dependent release of gliotransmitters by astrocytes plays an important role in synaptic transmission and plasticity, the role of astrocytes in motor-skill learning is not known. To ...