Since the inception of Medicaid in 1965, the program has seen extraordinary growth in expenditures and enrollment. From 1989 to 1992, the increases in Medicaid spending were the largest since the program began in. Enrollment in Medicaid by AFDC families grew from 3.8 million in 1990 to 4.4 million in 1992, almost a nine percent annual increase (Coughlin et al. 1994). During this period, states ...

Pfam 30 (16,306 HMMs) provides the PfamA.full.uniprot file that corresponds to UniProt 2016_02 (46,974,580 proteins). This file was used to obtain dPUC2’s observed family pair counts, CODD’s list of certified domain pairs [1], and DAMA’s domain information and observed architectures [2]. We used the HMMER 3.1b2 version of hmmscan to predict domains (this version is required by Pfam 30). We down...

Databases of multiple sequence alignments are a valuable aid to protein sequence classification and analysis. One of the main challenges when constructing such a database is to simultaneously satisfy the conflicting demands of completeness on the one hand and quality of alignment and domain definitions on the other. The latter properties are best dealt with by manual approaches, whereas complet...

According to one view, government welfare programs of the last two decades (principally Aid to Families with Dependent Children, AFDC) have succeeded in aiding some groups but have left a residue of persons destined to perennial dependence on public support. Made up for the most part of the adult children of "welfare mothers," this subgroup has sometimes been portrayed as deficient not only in ...

Calpains are ubiquitous and well-conserved proteins that belong to the calcium-dependent, non-lysosomal cysteine protease family. In this study, 8 putative calpains were identified using Pfam domain analysis and BlastP searches in M. oryzae. Three single gene deletion mutants (ΔMocapn7, ΔMocapn9 and ΔMocapn14) and two double gene deletion mutants (ΔMocapn4ΔMocapn7 and ΔMocapn9ΔMocapn7) were obt...

We consider the estimation of nonlinear models with mismeasured explanatory variables, when information on the marginal distribution of the true values of these variables is available. We derive a semi-parametric MLE that is is shown to be √ n consistent and asymptotically normally distributed. In a simulation experiment we find that the finite sample distribution of the estimator is close to t...

In late fall 1984, more than 110,000 Wisconsin Aid to Families with Dependent Children (AFDC) Medicaid recipients were enrolled in health maintenance organizations (HMO's). Capitation rates were set by competitive bidding, subject to a rate ceiling. Planners considered whether to adjust the rates to account for demographic changes in the AFDC population between the time that data for the rate c...

The Abi protein family consists of putative membrane-bound metalloproteases. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes (e.g., pln locus from Lactobacillus plantarum and sag locus from Streptococcus pyogenes), whe...

The current official U.S. poverty measure has been not only an important statistical indicator; it has also had direct policy uses in government programs that are designed to help low-income families whose resources fall below a standard of need. Many programs have their own need standard for eligibility, but a significant number link their standard to the official poverty thresholds (or a mult...

Welfare reform has transformed a needs-based family income support into temporary assistance for persons entering the workforce. This paper uses observations from an ethnographic study covering the period from 1995-2001 to examine the impact on drug-using welfare-needy households in inner-city New York. The analysis suggests that studies may underestimate the extent to which substance use is as...