INTRODUCTION AND OBJECTIVES High-sensitivity troponin assays have improved the diagnosis of acute coronary syndrome in patients presenting with chest pain and normal troponin levels as measured by conventional assays. Our aim was to investigate whether N-terminal pro-brain natriuretic peptide provides additional information to troponin determination in these patients. METHODS A total of 398 p...

the $k$-th semi total point graph $r^k(g)$ of a graph $g$, is a graph obtained from $g$ by adding $k$ vertices corresponding to each edge and connecting them to endpoint of edge considered. in this paper, we obtain formulae for the resistance distance and kirchhoff index of $r^k(g)$.

Composite endpoints, consisting of the union of two or more outcomes, are often used as the primary endpoint in time-to-event randomized clinical trials. Previously, Gómez and Lagakos provided a method to guide the decision between using a composite endpoint instead of one of its components when testing the effect of a treatment in a randomized clinical trial. Consider the problem of testing th...