Protein supplementation may be an alternative to reduce the erosive potential of acidic drinks. The aim of this in vitro study was to evaluate the erosive potential of an orange juice modified by dietary proteins. A commercially available orange juice was added 0.2 g/L casein, 2.0 g/L ovalbumin and their combination. The juice with no additives and a commercially available calcium-modified juic...

The proteins of developing dental enamel matrix, although among the least studied of all the extracellular proteins, have nevertheless been found to possess certain unique and interesting properties. The amino acid composition has been characterized by the highest content of proline thus far reported for any protein (approx. 200-250 residues/1000 amino acid residues), a relatively large number ...

BACKGROUND Matrix metalloproteinases (MMPs) degrade the extracellular matrix (ECM) and regulate remodeling and regeneration of bone. Enamel matrix derivative (EMD) protein has been used clinically for periodontal regeneration, although its molecular mechanisms are not clear. We evaluated the role of matrix metalloproteinases (MMPs) in regulating EMD-dependent degradation of gelatin on oeoblast-...

Following a review of periodontal wound healing, this article discusses techniques designed to optimise including guided-tissue regeneration and using enamel matrix derivatives. Enamel derivatives are porcine derived, thought stimulate differentiation, proliferation, migration mineralization in cells found tissues. This charts the development surgical outcomes from regenerative techniques, addi...

We have explored the role of Wnt signaling in dentinogenesis of mouse molar teeth. We found that Wnt10a was specifically associated with the differentiation of odontoblasts and that it showed striking colocalization with dentin sialophosphoprotein (Dspp) expression in secretory odontoblasts. Dspp is a tooth specific non-collagenous matrix protein and regulates dentin mineralization. Transient o...

The identification of genes with selective expression in specific organs or cell types provides an entry point for understanding biological processes that occur uniquely within a particular tissue. Using a subtraction approach designed to identify genes preferentially expressed in specific tissues, we have identified prostase, a human serine protease with prostate-restricted expression. The pro...