Pesticides may be involved in oyster summer mortality events, not necessarily as a single causative agent but as an additional stressor. In this context, the present study aimed to assess the toxicity of glyphosate, its by-product, aminomethylphosphonic acid (AMPA) and two commercial formulations, Roundup Express(®) (R(EX)) and Roundup Allées et Terrasses(®) (R(AT)), containing glyphosate as th...

During pregnancy, a fetus can be affected by exposure to a variety of chemicals and pharmaceuticals. These effects can occur through exposure of the mother and subsequent placental transport. Thus, it is important to assess embryotoxicity (developmental toxicity without the observation of maternal toxicity) and teratogenicity (irreversible structure developmental effects without the observation...

Abstract Previous studies have suggested that arsenic crosses the placenta and affects fetus development. The study under consideration aims to show comparative ameliorative effect of Moringa oleifera leaf flower extracts against sodium arsenate induced toxicity mice. Pregnant mice (N=44) were kept in lab divided into eleven group from (A K) orally administered doses 6 mg/kg, 12 mg/kg for arsen...

Groups of up to 13 pregnant rats were individually caged. Body weight, food and water consumption were recorded at days 1, 8, 15 and 22 of gestation and the dams were treated on days 8-15 with sodium chlorite, 0.1%, 0.5% or 2% in drinking water or by injection of 10, 20, or 50 mg/kg IP or by gavaging with 200 mg/kg. To prevent ingestion of stillborn pups some dams were sacrificed at day 22. Oth...

We have studied the teratogenicity of benzo(a)pyrene (BP), benzo(a)pyrene-4,5-oxide, and a racemic mixture of 7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene, a proximal metabolite and ultimate carcinogenic metabolite of BP, respectively, and of 6-methylbenzo(a)pyrene after direct injection into embryonal Swiss mice. The compounds were dissolved in acetone and ...