Duplication anomalies are quite common with ureteral duplication anomalies being the most frequent. Despite the relatively frequent incidence of a horseshoe kidney and duplication anomalies in any individual patient, the combination of horseshoe kidney and bilateral ureteric duplication is a very rare entity and very few cases have been reported to date. We present a case of a patient with a no...

In this PhD project, we deal with the issue of code duplication in logic programs. In particular semantical duplication or redundancy is generally viewed as a possible seed of inconvenience in all phases of the program lifecycle, from development to maintenance. The core of this research is the elaboration of a theory of semantical duplication, and of an automated program analysis capable of de...

A second exploratory laparotomy in our unit revealed duplication of entire colon up to the lower rectum. The terminal ileum was seen to enter the normal large bowel and the three parallel appendices were attached to the duplication, which was on the anterior side. We found that the duplication did not communicate with the normal bowel at the distal end by injecting saline into its distal end wh...

The yeast Mps1p protein kinase acts in centrosome duplication and the spindle assembly checkpoint. We demonstrate here that a mouse Mps1p ortholog (esk, which we designate mMps1p) regulates centrosome duplication. Endogenous mMps1p and overexpressed GFP-mMps1p localize to centrosomes and kinetochores in mouse cells. Overexpression of GFP-mMps1p causes reduplication of centrosomes during S phase...

We developed a recurrence relation that counts the number of tandem duplication trees (either rooted or unrooted) that are consistent with a set of n tandemly repeated sequences generated under the standard unequal recombination (or crossover) model of tandem duplications. The number of rooted duplication trees is exactly twice the number of unrooted trees, which means that on average only two ...

Gene duplication is widely believed to facilitate adaptation, but unambiguous evidence for this hypothesis has been found in only a small number of cases. Although gene duplication may increase the fitness of the involved organisms by doubling gene dosage or neofunctionalization, it may also result in a simple division of ancestral functions into daughter genes, which need not promote adaptatio...

The Minimum Duplication problem is a well-known problem in phylogenetics and comparative genomics. Given a set of gene trees, the Minimum Duplication problem asks for a species tree that induces the minimum number of gene duplications in the input gene trees. Recently, a variant of the Minimum Duplication problem, called Minimum Duplication Bipartite, has been introduced, where the goal is to f...

Enteric duplication is an ectopic cyst or a tubular structure composed of smooth muscles surrounding mucosa of the gastrointestinal tract (1). Most cases of duplication are present before the age of 2 years as an acute abdomen or bowel obstruction (2). Diagnosis of duplication cyst is uncommon in adults, and enteric duplication within the pancreas is especially uncommon and difficult to diagnos...