The paper describes the design, implementation, and evaluation of Depot, a cloud storage system that minimizes trust assumptions. Depot tolerates buggy or malicious behavior by any number of clients or servers, yet it provides safety and liveness guarantees to correct clients. Depot provides these guarantees using a two-layer architecture. First, Depot ensures that the updates observed by corre...

Abstract A DP-TABU algorithm is proposed which can effectively solve the multi-line scheduling problem of single Deport (SD-ML-VSP). The regional coordinated dispatch single-line deport bus to problems idle low-peak vehicles and insufficient peak capacity in scheduling. multiple lines at same station adjusted realize resource sharing such as timetables, vehicles, drivers. Shared departure inter...

Using pigmented rabbits, two fluorophotometric methods for measuring aqueous flow were compared. A corneal depot of dye was used to measure aqueous flow in one eye of each rabbit while the vitreous depot method of Johnson and Maurice was used to measure aqueous flow over the same period in the fellow eye. After intravenous administration of acetazolamide or mannitol, during the first hour after...

Vehicle Routing Problems (VRPs) are prevalent in all large pick up and delivery logistics systems and are critical to city logistics operations. Of notable significance are three key extensions to classical VRPs: (1) multi-depot scenario; (2) probabilistic demand; and (3) time-window constraints, which are considered simultaneously with VRPs in this paper. The issue then becomes a Multi Depot P...

Title of dissertation: INTEGER PROGRAMMING-BASED HEURISTICS FOR VEHICLE ROUTING PROBLEMS Damon J. Gulczynski Doctor of Philosophy, 2010 Dissertation directed by: Professor Bruce Golden Applied Mathematics and Scientific Computation Robert H. Smith School of Business The vehicle routing problem (VRP) has been an active field of study by operations researchers for over 50 years. Many practical ap...

A new depot formulation of the LHRH analogue Zoladex (goserelin acetate) has been developed which releases the drug over a period of at least 3 months as judged by measurement of drug content in depots at intervals after insertion in male rats and by the suppression of oestrogen secretion and oestrus in female rats. This formulation is based on the lactide/glycolide polymer system used for the ...

BACKGROUND The size and geometry of an insulin depot that is formed during subcutaneous administration by an insulin pump is evaluated. A novel method is used to visualize accurately the depot formation for small volumes of insulin (of the order of 10-100 µl) at a given point in time. Conventional visualization methods such as magnetic resonance imaging are unable to provide such accurate measu...

AIMS The aim was to assess the pharmacokinetics, pharmacodynamics, safety and tolerability of octreotide subcutaneous (s.c.) depot, a novel octreotide formulation. METHODS This was a phase I, randomized, open label study. After a single dose of octreotide immediate release (IR) 200 µg, subjects were randomized to one of eight groups to receive three monthly injections of octreotide s.c. depot...