Current means of measuring RT-induced fibrosis are subjective. We evaluated the DermaLab suction cup system to measure objectively skin deflection as a surrogate for fibrosis. Sixty-nine patients with E-STS were treated with limb-sparing surgery and 50-66 Grays (Gy) of RT. Using a "scleroderma" DermaLab Suction Cup, the skin stiffness was measured by two clinicians. The National Cancer Institut...

The emergence of commercial wireless devices based on ultra-wideband radio technology (UWB-RT) is widely awaited and anticipated. UWB-RT is not only applicable to communications, imaging and ranging, it also promises to alleviate the problem of increasingly scarce spectrum resources while enabling new wireless applications and business opportunities. These prospects have caught the early attent...

In an RT experiment, subjects were asked to respond with minimal responses to prerecorded dialogs and a manipulated version of these dialogs that contained only intonation and pause information. Response delays and, especially, variances were higher to the impoverished, intonation only, stimuli than to the original recordings. It was also found that intonation only utterances ending in a mid-fr...

In a reaction time (RT) task 40 subjects were told to react to the onset of a 6-second shock. Following l0 trials, half of the subjects were told that by decreasing their RT they would reduce shock duration. Remaining subjects were simply told that shock duration would he reduced. All subjects, regardless of group assignment or RT, received 3-second shocks in the second half of the study. Durin...

Topical fungal infections can become severe if left untreated. Efficient treatment modalities for topical fungal infections aid the penetration of antifungal agents deep into viable skin layers. Terbinafine is a fungicidal agent that inhibits ergosterol, an essential fungal component. The main objective of this study was to evaluate skin permeation and retention of a terbinafine-loaded solution...


 Many differentially expressed genes associated with feather colour in quail embryos can be screened using RNA-seq technology. The aim of this study was to verify the accuracy RT-qPCR. transcriptome embryonic skin tissues quails were sequenced by Illumina HiSeq TM2000 sequencing platform. As a result, 2512 found. Among them, 950 up-regulated white-feather embryos, and 1562 down-regulated....

Studies of RT as definitive treatment in primary and recurrent skin cancers consistently report high rates of local control despite extremely variable total doses and fractionation schedules [1-6]. With the increase of life expectancy, many patients develop second primary tumors within or close to previous RT area or late in-field recurrences [7]. Moreover, surgical options are frequently compr...

A third-generation fluoroquinolone, pradofloxacin (PRA), is currently being developed to treat bacterial infections in dogs. The purpose of this study was to assess the clinical efficacy in 20 dogs affected with superficial and deep pyoderma. An initial aerobic skin culture was performed in dogs with superficial pyoderma; aerobic/anaerobic tissue culture was performed in dogs with deep pyoderma...

Lymphedema (tissue swelling caused by an accumulation of lymph fluid) in the lower legs is relatively common elderly people. Dermal fibrosis and hyperkeratotic verrucous lesions setting long-standing lymphedema, called elephantiasis verrucosa nostra, can develop some patients, although mechanisms underlying these tissue changes are unknown. Here, we studied effects lymphedema on skin using k-cy...