نتایج جستجو برای: cry gene

تعداد نتایج: 1143884  

Journal: :Cell 2002
Nicolas Preitner Francesca Damiola Luis-Lopez-Molina Joszef Zakany Denis Duboule Urs Albrecht Ueli Schibler

As the period length of this pacemaker is only approximately 24 hr, the circadian clock has to be reset every day by an input pathway in order to remain in resonance with geophysical time. This synchronization Division of Biochemistry Animal circadian rhythms appear to be generated by University of Fribourg feedback loops in gene expression that include both Rue du Musé e 5 transcriptional and ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Qi Cao Xuan Zhao Jingwen Bai Sigal Gery Haibo Sun De-Chen Lin Qi Chen Zhengshan Chen Lauren Mack Henry Yang Ruishu Deng Xianping Shi Ling-Wa Chong Han Cho Jianjun Xie Quan-Zhen Li Markus Müschen Annette R Atkins Christopher Liddle Ruth T Yu Serhan Alkan Jonathan W Said Ye Zheng Michael Downes Ronald M Evans H Phillip Koeffler

The circadian system regulates numerous physiological processes including immune responses. Here, we show that mice deficient of the circadian clock genes Cry1 and Cry2 [Cry double knockout (DKO)] develop an autoimmune phenotype including high serum IgG concentrations, serum antinuclear antibodies, and precipitation of IgG, IgM, and complement 3 in glomeruli and massive infiltration of leukocyt...

Journal: :Journal of invertebrate pathology 2014
Margaret C Wirth Colin Berry William E Walton Brian A Federici

The interaction of Mtx toxins from Lysinibacillus sphaericus (formerly Bacillus sphaericus) with Bacillus thuringiensis subsp. israelensis Cry toxins and the influence of such interactions on Cry-resistance were evaluated in susceptible and Cry-resistant Culex quinquefasciatus larvae. Mtx-1 and Mtx-2 were observed to be active against both susceptible and resistant mosquitoes; however varying l...

2016
C. F. Zachariah Radhika Rani

A new approach has been proposed to design of an automatic infant cry recognition system based on the fuzzy transform (F-transform) that classifies two different kinds of cries, which come from physiological status and medical disease. Feature extraction and development of classification algorithms play an important role in the area of automatic analysis of infant cry signals. F-transform is th...

Journal: :Applied and environmental microbiology 2012
Weixing Ye Lei Zhu Yingying Liu Neil Crickmore Donghai Peng Lifang Ruan Ming Sun

We have designed a high-throughput system for the identification of novel crystal protein genes (cry) from Bacillus thuringiensis strains. The system was developed with two goals: (i) to acquire the mixed plasmid-enriched genomic sequence of B. thuringiensis using next-generation sequencing biotechnology, and (ii) to identify cry genes with a computational pipeline (using BtToxin_scanner). In o...

Journal: :International immunopharmacology 2007
Motohiko Suzuki Nobuo Ohta Wei-Ping Min Tamami Matsumoto Rui Min Xusheng Zhang Kazunori Toida Shingo Murakami

Immunotherapy using T-cell epitope peptides or CpG DNA conjugated with allergenic protein is useful, although the mechanisms of these therapies differ. However, the combination of CpG DNA and peptide, but not protein, had not been documented. Therefore, we investigated CpG DNA conjugated with peptide to obtain positive synergistic effects. In the first experiment, mice were vaccinated with a co...

Journal: :Cold Spring Harbor symposia on quantitative biology 2007
S M Reppert

The circadian clock has a vital role in monarch butterfly (Danaus plexippus) migration by providing the timing component of time-compensated sun compass orientation, which contributes to navigation to the overwintering grounds. The location of circadian clock cells in monarch brain has been identified in the dorsolateral protocerebrum (pars lateralis); these cells express PERIOD, TIMELESS, and ...

Journal: :Journal of invertebrate pathology 2005
Brian A Federici

The discovery and study of insecticidal bacteria, which began a little over a century ago, led to the development of commercial bacterial insecticides in the middle of the century that became the first successful and widely used microbial control agents. Most of these products were based on Bacillus thuringiensis, a bacterium that kills insects through the use of insecticidal proteins that subs...

Journal: :Current Biology 2013
Carla Gentile Hana Sehadova Alekos Simoni Chenghao Chen Ralf Stanewsky

BACKGROUND In nature, both daily light:dark cycles and temperature fluctuations are used by organisms to synchronize their endogenous time with the daily cycles of light and temperature. Proper synchronization is important for the overall fitness and wellbeing of animals and humans, and although we know a lot about light synchronization, this is not the case for temperature inputs to the circad...

Journal: :Research in Microbiology 2021

In Bacillus subtilis, motility genes are expressed in a hierarchical pattern – governed by the σD transcription factor and other proteins such as EpsE molecular clutch SlrA/SlrR regulator proteins. contrast, motile species cereus group seem to express their non-hierarchical pattern, less is known about regulation, also given that no orthologs σD, EpsE, SlrA or SlrR found B. genomes. Here we sho...

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