In topical administration of antifungals, the drugs should pass the stratum corneum to reach lower layers of the skin in effective concentrations. Thus, the formulation of antifungal agents into a suitable delivery system is important for the topical treatment of fungal infections. Nanosized colloidal carriers have gained great interest during the recent years to serve as efficient promoters of...

Mixing two immiscible liquids (such as oil and water) using emulsifier and energy inputs has been the matter of study for decades. In early 1890’s extensive work have been carried out on macroemulsions (i.e. oil dispersed in water in the form of fine droplets or vice versa) (Becher, 1977) and several theories and methods of their formation have been vastly explored (Lissant 1976 and 1984). Howe...

Nanoemulsions are submicron sized emulsions that are under investigation as drug carriers for improving the delivery of therapeutic agents. These are the thermodynamically stable isotropic system in which two immiscible liquids are mixed to form a single phase by means of appropriate surfactant and cosurfactant. Nanoemulsion droplet sizes fall typically in the range of 20200nm and shows narrow ...

In this study, pseudoternare phase diagrams were made and oil: water: surfactant: cosurfactant (O:W:S:CoS) weight ratios corresponding to microemulsion states were highlighted. Soybean oil was used as the oily phase (O) and a mixture of water and glycerol in a ratio of 4:1 (wt / wt) was used as the aqueous phase (W). As a surfactant (S) was used sorbitan monooleate (Span 80) and cosurfactants (...

The main purpose of this study was to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution rate. In this study, liquid SNEDDS containing Olmesartan was formulated and further developed into a solid form by the spray drying technique using Aerosil 200 as a solid carrier. Based on the preliminary screening of di...

Administration of drug by oral route is the most effective and acceptable route as it has better therapeutic efficacy, low cost and good patient compliance. More than 40% of new drugs are poorly water soluble. These drugs present development challenges and also have poor bioavailability. Although many formulation approaches like solid dispersions, complexation, pH modification exist, novel lipi...

A screening test used to help select surfactant systems potentially effective for oil recovery is to identify those formulations that yield middle-phase microemulsions when mixed with sufficient quantities of oil and brine. A correlation is presented to link these variables regarding their contributions to middle-phase formation: structure of the sulfonated surfactant, alkane carbon number (ACN...

| References | Full Text: HTML, PDF (Size: 554K) Save Article Study of the Biosynthesis of 1-Octen-3-ol Using a Crude Homogenate of Agaricus bisporus in a Bioreactor (p C135-C139) R.O. Morawicki, R.B. Beelman Published Online: Feb 6 2008 12:00AM DOI: 10.1111/j.1750-3841.2007.00660.x Abstract | References | Full Text: HTML, PDF (Size: 508K) Save Article Properties of High-Oleic Palm Oils Derived...

Recently, much attention has been paid to the preparation of polymeric nanoparticles in the size range of 10-100 nm. The microemulsion polymerization of polystyrene is a typical example.1-10 It has been shown that the particle size can be quantitatively controlled by the initial fleet ratio, namely the macroscopic surfactant-to-monomer weight ratio.1,8-10 A normal microemulsion contains at leas...

Motivated by numerous X-ray scattering studies of lamellar phases with membrane proteins, amphiphilic peptides, polymers, or other inclusions, we have determined the modifications of the classical Caillé law for a smectic phase as a function of the nature and concentration of inclusions added to it. Besides a fundamental interest on the behavior of fluctuating systems with inclusions, a precise...