PURPOSE To investigate the contribution of matrix metalloproteinases (MMPs) to recurrent corneal melting in keratoconjunctivitis sicca associated with primary Sjörgen's syndrome (pSS). METHODS One native melted cornea and ten melted corneal grafts from two patients with severe pSS were used. The presence of MMPs (1, 2, 3, 7, 8, 9, and 13) was detected using indirect enzyme immunohistochemistr...

Corneal collagen crosslinking (CCC)with riboflavin/ ultraviolet-A (UV-A) is a new therapeutic technique designed to strengthen the cornea and arrest progressive corneal ectasia. Few complications have been reported following this therapy. We report the case of a 40-year-old patient who had CCC for progressive keratectasia secondary to keratoconus. The patient had no medical history of systemic ...

abstract background: keratoconus is a bilateral corneal disease, which one way to cure it is to transplant. the transplantation may be rejected by recipient's immune system, which leads to failure of the graft. this study aimed to analysis the factors affecting bilateral corneal graft rejection based on copula function. methods: a sample of bilateral graft rejection times was assessed. since co...

Objective- This study was performed to evaluate and compare grossly and pathologically two surgical techniques of amniotic membrane patching on experimental corneal alkali burn in dogs.   Design- Experimental study.   Animals- Fifteen healthy dogs   Procedures- The central corneas of the dogs were inflicted by applying a round filter paper, 6.0 mm in diameter, soaked in 1 N NaOH for 60 sec. ...

purpose : to determine the efficacy of fibrin glue in corneal perforations up to 3 mm in diameter methods : a case series study was performed on corneal perforations up to 3 mm who were admitted at farabi hospital- tehran. age, visual acuity, presence and size of corneal thinning, corneal epithelial defect, size and depth of corneal infiltration, site and size of corneal perforation, corneal va...

purpose: to determine the sensitivity and specificity of posterior corneal elevation in discriminating keratoconus and subclinical keratoconus from normal corneas by galilei and orbscan ii diagnosed on the basis of topography. methods: three groups (keratoconus, subclinical keratoconus and normal) were evaluated with galilei and orbscan ii and results were compared to those obtained by gold sta...

purpose: to evaluate the efficacy of riboflavin administration and ultraviolet a (uva) cross-linking on advanced symptomatic bullous keratopathy (bk). methods: 10 patients with symptomatic pseudophakic bullous keratopathy (pbk) were included. slit-lamp examination, visual acuity, foreign body sensation (fbs) and corneal thickness as measured by pentacam, were performed before corneal cross-link...

purpose: to evaluate the ability to predict visual outcome after penetrating keratoplasty (pkp) in patients with pseudophakic or aphakic corneal edema (pce or ace). methods: medical records of 34 patients (34 eyes) who underwent pkp for pce or ace during 1994-2004 in ahvaz were retrospectively analyzed for variables in the history and ocular examination before pkp and visual outcome after pkp. ...

purpose : to compare central corneal thickness (cct), corneal endothelial cell density, and lens capsule thickness in normotensive patients with and without pseudoexfoliation syndrome (pxs) methods : this was a prospective, comparative, descriptive study. normotensive candidates for cataract surgery with (study group) and without (control group) pxs were enrolled in the study. cct and corneal e...