Background – The aim of present study was to investigate a possible link between the creatine kinase (CK) content in the V. xanthia raddei venom and its acute toxicity values. Methods – Creatine kinase, the ATP-generating enzyme belonging to a phosphotransferases family, has been completely purified from the venom of Vipera xanthia raddei using a novel method of affinity chromatography on ADP-S...

Lower gastrointestinal hemorrhage accounts for approximately 20% of gastrointestinal hemorrhage. The most common causes of lower gastrointestinal hemorrhage in adults are diverticular disease, inflammatory bowel disease, benign anorectal diseases, intestinal neoplasias, coagulopathies and arterio-venous malformations. Hemangiomas of gastrointestinal tract are rare. Mesenteric hemangiomas are al...

INTRODUCTION Vascular malformation is associated with coagulopathies, especially when hemostasis is challenged. CASE PRESENTATION We present the case of an 11-year-old Hispanic girl with Klippel-Trenaunay-Weber syndrome that developed disseminated intravascular coagulation after minor surgery, which was controlled by blood product transfusions and enoxaparin to address an ongoing consumptive ...

PROLOGUE The purpose of this review is to provide the pharmacy student with an overview of the therapeutic considerations in patients with acute renal failure that has not responded to preliminary interventions (e.g., fluid therapy for restoration of plasma volume in patients with hypovolemia-induced renal dysfunction). A taxonomical listing of goals and objectives is provided to direct the stu...

Postpartum hemorrhage, the loss of more than 500 mL of blood after delivery, occurs in up to 18 percent of births and is the most common maternal morbidity in developed countries. Although risk factors and preventive strategies are dearly documented, not all cases are expected or avoidable. Uterine atony is responsible for most cases and can be managed with uterine massage in conjunction with o...

Central venous access devices are used in many branched of medicine where venous access is required for either long-term or a short-term care. These guidelines review the types of access devices available and make a number of major recommendations. Their respective advantages and disadvantages in various clinical settings are outlined. Patient care prior to, and immediately following insertion ...

INTRODUCTION In general, pericardial diseases in small animal practice are rare, with pericardial effusion being the most commonly encountered pericardial disease. Septic pericarditis, although well recognised in cattle and humans, has rarely been reported in either the dog or cat. Septic pericarditis can result from pleural or pulmonary infections, secondary to trauma, or from haematogenous sp...

Dysfunctional uterine bleeding is very common in adolescents because of the high frequency of anovulatory cycles in this age group. The diagnosis of dysfunctional uterine bleeding is based on the exclusion of all the other causes of abnormal uterine bleeding in an adolescent. The most common causes of abnormal uterine bleeding include coagulopathies, pregnancy, trauma, and endocrinopathies. Men...