نتایج جستجو برای: cancer patients
تعداد نتایج: 2728287 فیلتر نتایج به سال:
Background: Cancer has the highest disease-related mortality rate in Iran. Reduced activity of paraoxonase reported in patients with cancer may be due to a reduction in its antioxidant properties and a subsequent increased risk of developing cancer. We aimed to assess antioxidant and oxidative status in patients with cancer through measuring the activity of PON1 as an antioxidant enzyme and det...
Background and purpose: Gastric cancer has been considered as the second lethal cancer throughout the world and the incidence of this cancer in Ïran is 25 in 10000 people per year. Ïnterleukin-11 (ÏL-11), a member of ÏL-6 family, may play some role in developing gastric cancer via activation of the JÂK/STÂT signaling pathway. Ïn this study, the level of ÏL-11 gene expression was determined in g...
Background and purpose : Ënhanced sensitivity to the chromosome-damaging effects of ionizing radiation is a feature of many cancer-predisposing conditions. Ïn this study we compared the radiation sensitivity of breast cancer patients and healthy volunteers by measuring the levels of initial DNÂ damage in peripheral leukocytes using the comet assay (single-cell alkaline gel electrophoresis). ...
absract gastric cancer is the fourth most common cancer and the second leading cause of cancer death. most cases are sporadic and only 10% of patients, show familial clustering. among these patients, 1 to 3 % have hereditary diffuse gastric cancer (hdgc), which is autosomal-dominant and present in younger ages. mutations in ecadherin gene cdh1 has been identified in 30 to 50% of patients. becau...
Background & objectives: Regarding the prevalence of psychological problems in cancer patients, some reports have shown the effectiveness of self-efficacy model to be superior to previous conventional psychological therapies for increasing the well-being of cancer patients. The aim of this study was to evaluate a self-efficacy education model on quality of life in patients with cancer at Urmia ...
Introduction: Gastric cancer is a major public health issue worldwide. The factors that initiate cancer are not well understood, however aberrant expression of genes is associated with this cancer. TRIP13 plays pivotal roles in meiotic recombination, DNA repair, and cell cycle progression. An increasing body of evidence suggests that TRIP13 may possess functions other than meiosis and mitosis, ...
Background and purpose: Çancer patients are usually suffering from severe pain and disrupted life style and using a proper analgesic seems to be the best option. Pain management failure or improper dosages of analgesics may lead to drug abuse or substance dependency in cancer patients. The purpose of this study was to determine the prevalence of drug abuse and substance dependency among cance...
aim : to evaluate the association of dnmt1 and mgmt amino acid substitution polymorphisms and colorectal cancer in iranian population. background : the mgmt and dnmt1 are two important methyltransferase enzymes. amino acid substitution polymorphisms in mgmt and dnmt1 genes may be associated with the genetic susceptibility to sporadic colorectal cancer. patients and methods : we assessed eight ...
conclusions our study revealed that patients with the diagnosis of breast cancer have greater bpe in comparison with control group. the results may be indicative for higher probability of developing breast cancer in patients with higher bpe. therefore, ce-mri could be a useful tool for breast cancer risk assessment. objectives background parenchymal enhancement (bpe) on contrast-enhanced magnet...
Background and purpose: Colorectal cancer is the fourth most common cancer in Iran. The incidence of this cancer, especially in the northern regions in Iran, has increased in the last two decades. This study was designed to update the demographic and clinical characteristics of patients with colorectal cancer in Mazandaran province. Materials and methods: All patients with diagnosis of colorec...
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