Purpose: The aim of the present study was to investigate the effect of chitosan molecular weight on size, size distribution, release rate, mucoadhesive properties and electrostatic bonding of alginate/chitosan microparticles containing prednisolone Methods: Three mucoadhesive alginate/chitosan microparticle formulations, f1, f2 and f3, were prepared using low, medium and high chitosan molecular...

A new carotenoid-rich product was formed by entrapment of Dunaliella salina in calcium alginate beads of di†erent alginate concentrations, followed by drying in a Ñuid-bed dryer. The drying process yielded b-carotene recoveries of between 79 and 89% and produced a change in the 9-cis/all-trans ratio of b-carotene isomers. The carotenoid stability of the product was dependant on both the storage...

Sodium alginate is a seaweed-derived fibre that has previously been shown to moderate appetite in models of acute feeding. The mechanisms underlying this effect may include slowed gastric clearance and attenuated uptake from the small intestine. In order to assess whether alginate could be effective as a means of appetite control in free-living adults, 68 males and females (BMI range: 18.50-32....

The purpose of this research was to prepare floating calcium alginate beads of berberine for targeting the gastric mucosa and prolonging their gastric residence time. The floating beads were prepared by suspending octodecanol and berberine in sodium alginate (SA) solution. The suspension was then dripped into a solution of calcium chloride. The hydrophobic and low-density octodecanol enhanced t...

Nowadays in orthopedic surgery -in the treatment of bone and soft tissue infectionsthere is an increasing claim for improving biodegradable drug delivery systems that can be easily placed into the site of application instead of the currently applied polymethylmethacrylate (PMMA) bone cements, since PMMA has some undesirable side effects. Therefore the aim of the study was to develop an injectab...

The present work describes the synthesis of novel injectable, self-setting bone cements made of strontium-substituted hydroxyapatite (Sr-HA), obtained by single-phase calcium phosphate precursors doped with different amounts of strontium and enriched with alginate. The addition of alginate improved the injectability, cohesion, and compression strength of the cements, without affecting the harde...

The World Health Organization has called for new effective and affordable alternative antimicrobial materials the prevention treatment of microbial infections. In this regard, calcium alginate previously been shown to possess antiviral activity against enveloped double-stranded DNA herpes simplex virus type 1. However, non-enveloped viruses are more resistant inactivation than ones. Thus, viral...

background sulfur oxides released from the burning of oil causes severe environmental pollution. the sulfur can be removed via the 4s pathway in biodesulfurization (bds). immobilization approaches have been developed to prevent cell contamination of oil during the bds process. objectives the encapsulation of rhodococcus erythropolis r1 in calcium alginate beads was studied in order to enhance c...

Nanoformulation consisting of Streptomycin loaded chitosan-alginate nanoparticles were prepared using ionotropic-pregelation method and optimization was done in terms of polymer concentration, crosslinker concentration and stirring time. The optimal parameters were found to be Chitosan 0.75mg/ml, calcium chloride 1% (w/v) and stirring time 90 min. Polymer (chitosan and sodium-alginate) and cros...

Ginger has a high moisture content, which makes it highly susceptible to spoilage. Therefore, the shelf life can be extended through drying. In drying process, osmotic dehydration is applied as pre-treatment due its simple operation and energy-saving process for removing from food. However, large solute gain during become major challenge of this negative impact on final product. The edible coat...