نتایج جستجو برای: cad pathogenesis

تعداد نتایج: 143211  

2011
Yuan Zhou Yutao Wei Lei Wang Xianguo Wang Xinling Du Zongquan Sun Nianguo Dong Xinzhong Chen

BACKGROUND Disorders of endocrine substances in epicardial adipose tissue are known causes of coronary artery disease (CAD). Adiponectin is associated with cardiovascular disease. However, expression of adiponectin in epicardial adipose tissue and its function in CAD pathogenesis is unclear. This study investigates adiponectin expression in epicardial adipose tissue in CAD patients. METHODS V...

Journal: :Arthritis Research & Therapy 2005
Kenneth J Warrington Peter D Kent Robert L Frye James F Lymp Stephen L Kopecky Jörg J Goronzy Cornelia M Weyand

The risk for cardiovascular (CV) disease is increased in rheumatoid arthritis (RA) but data on the burden of coronary atherosclerosis in patients with RA are lacking. We conducted a retrospective case-control study of Olmsted County (MN, USA) residents with RA and new-onset coronary artery disease (CAD) (n = 75) in comparison with age-and sex-matched controls with newly diagnosed CAD (n = 128)....

Journal: :Folia biologica 2005
J Kirbis D Kese D Petrovic

Many authors have shown an association between Chlamydia pneumoniae (CPn) infection and coronary artery disease (CAD). However, whether CPn infection demonstrated by CPn DNA presence in the artery wall plays an important role in pathogenesis of CAD and acute coronary events (i.e. unstable angina) remains to be elucidated. One hundred and fifteen consecutive patients with CAD (51 with unstable a...

Journal: :Diabetes Care 2009
David Eddy Len Schlessinger Richard Kahn Barbara Peskin Rick Schiebinger

OBJECTIVE People with diabetes have an increased risk of coronary artery disease (CAD). An unanswered question is what portion of CAD can be attributed to insulin resistance, related metabolic variables, and other known CAD risk factors. RESEARCH DESIGN AND METHODS The Archimedes model was used to estimate the proportion of myocardial infarctions that would be prevented by maintaining insulin...

Journal: :Circulation. Cardiovascular genetics 2009
Hu Ding Yujun Xu Xiaojing Wang Qi Wang Lan Zhang Yuanchao Tu Jiangtao Yan Wei Wang Rutai Hui Cong-Yi Wang Dao Wen Wang

BACKGROUND Recent studies on genome-wide association have identified common variants on chromosome 9p21 associated with coronary artery disease (CAD). Given that ischemic stroke and CAD share several aspects of etiology and pathogenesis, we investigated the association of variants on chromosome 9p21 with ischemic stroke and CAD in the Chinese Han population by capturing the majority of diversit...

Journal: :Circulation research 2016
Salim S Hayek James MacNamara Ayman S Tahhan Mosaab Awad Adithya Yadalam Yi-An Ko Sean Healy Iraj Hesaroieh Hina Ahmed Brandon Gray Salman S Sher Nima Ghasemzadeh Riyaz Patel Jinhee Kim Edmund K Waller Arshed A Quyyumi

RATIONALE Peripheral arterial disease (PAD) is a clinical manifestation of extracoronary atherosclerosis. Despite sharing the same risk factors, only 20% to 30% of patients with coronary artery disease (CAD) develop PAD. Decline in the number of bone marrow-derived circulating progenitor cells (PCs) is thought to contribute to the pathogenesis of atherosclerosis. Whether specific changes in PCs...

Journal: :Tropical Journal of Pharmaceutical Research 2022


 Purpose: To examine the role of miR-557 in pathogenesis and development glioblastoma (GBM) its potential regulatory mechanism.
 Methods: Dysregulation GBM cells was determined using quantitative (real-time) PCR (qPCR). Cell proliferative ability, migratory activity invasive ability were measured MTT colorimetric assay, wound healing assay Transwell chambers assay. The direct target ...

Journal: :European Heart Journal 2022

Abstract Background Dyslipidaemia promotes atherosclerosis. Genetic dyslipidaemias, Familial Hypercholesterolaemia (FH) being the most common, are associated with heightened risk of coronary artery disease (CAD) and premature major adverse cardiovascular events (MACE). However, this is both heterogeneous modifiable treatment. CT imaging can identify subclinical atherosclerosis, enabling persona...

2017
Jiny Nair Vijay V. Kakkar Jayashree Shanker

BACKGROUND & OBJECTIVES Metabolic syndrome (MetS) increases the likelihood of developing coronary artery disease (CAD), and inflammation is involved in the pathogenesis of both these conditions. The present work was conducted to examine the relative expression of 18 key inflammatory genes associated with MetS and incident CAD in a representative group of patients. METHODS A total of 178 male ...

عباسیان, سهیلا, فیروزرای, محسن,

ABSTRACT Coronary artery disease (CAD) is the leading cause of death among non-insulin dependant diabetic (NIDDM) Patients. One of risk factor for CAD in dyslipidemia. In regards to high prevalence of NIDDM and CAD among our people, in the present study, levels of lipids and lipoproteins in two groups of patients, CAD+/NIDDM+ group and CAD+/NIDDM- group, were evaluated and compared. ...

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