نتایج جستجو برای: c down

تعداد نتایج: 1238707  

2013
Moran Elboim Inna Grodzovski Esther Djian Dana G. Wolf Ofer Mandelboim

Both NK cells and CTLs kill virus-infected and tumor cells. However, the ways by which these killer cells recognize the infected or the tumorigenic cells are different, in fact almost opposite. CTLs are activated through the interaction of the TCR with MHC class I proteins. In contrast, NK cells are inhibited by MHC class I molecules. The inhibitory NK receptors recognize mainly MHC class I pro...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2006
Akihiro Yano Yasuhisa Fujii Aki Iwai Satoru Kawakami Yukio Kageyama Kazunori Kihara

PURPOSE Glucocorticoids such as prednisone, hydrocortisone, and dexamethasone are known to provide some clinical benefit for patients with hormone-refractory prostate cancer. However, the underlying mechanisms by which glucocorticoids affect hormone-refractory prostate cancer progression are not well established as yet. Our previous study has shown that glucocorticoids inhibit tumor angiogenesi...

Journal: :The Journal of pharmacology and experimental therapeutics 1998
M Yang R Büscher K Taguchi B Grübbel P A Insel M C Michel

We examined the down-regulation of alpha-1B adrenoceptors in Madin-Darby canine kidney D1 (MDCK) cells with an emphasis on a possible role of protein kinase C. The alpha-1 adrenoceptor agonist phenylephrine (1-100 microM) concentration-dependently down-regulated alpha-1B adrenoceptors in MDCK cells. Down-regulation by 100 microM phenylephrine was detectable after 2 hr and maximal after 8 to 24 ...

Procambarus clarkii crayfish has been developed as an excellent animal model to study the characteristics and pathogenesis of white spot syndrome virus and the host defense mechanisms of crustacean. However, due to pathogen infections of crayfish in Chinese farms, research based on this model has been slowed down. Using triplex polymerase chain reaction, we found the virulence Aeromonas hydroph...

Journal: :iranian rehabilitation journal 0
farideh dehghani university of social welfare and rehabilitation sciences, tehran, iran. fariba yadegari university of social welfare and rehabilitation sciences, tehran, iran. enayatollah bakhshi university of social welfare and rehabilitation sciences, tehran, iran. mehdi dehghan babol medical sciences university, babol, iran.

objectives: reading is a language skill based on visual modality which recently is addressed as a facilitator of expressive language in children with down syndrome. the aim was designing a whole word reading protocol and examining its effects on the language skills of children with down syndrome. methods: a whole word reading protocol was developed and was examined through a single-subject stud...

Objective(s): Non-invasive treatment options for retinoblastoma (RB), the most common malignant eye tumor among children, are lacking. Epithelial growth factor receptor (EGFR) accelerates cell proliferation, survival, and invasion of many tumors including RB. However, RB treatment by targeting EGFR has not yet been researched. In the current study, we investigated the effect of EGFR down-regula...

Journal: :iranian journal of otorhinolaryngology 0
faramarz memari ent and head & neck research center, hazrat rasoul akram hospital, iran university of medical sciences, tehran, iran. mojtaba maleki delarestaghi department of otolaryngology and head and neck surgery. firoozgar clinical research development center, firoozgar hospital, iran university of medical sciences, tehran, iran. parisa mir department of otolaryngology and head and neck surgery. firoozgar clinical research development center, firoozgar hospital, iran university of medical sciences, tehran, iran. mohammad golmohammadi department of internal medicine. shohada medical center, shahid beheshti university of medical sciences, ehsan shams koushki ent and head & neck research center, hazrat rasoul akram hospital, iran university of medical sciences, tehran, iran.

introduction: meatoplasty is the final and essential step in performing effective canal wall down surgery for chronic otitis media. in this article we review some previous techniques and discuss our preferred method. materials and methods: in this observational case series study, we used this technique in 53 patients (28 male and 25 female) between january 2005 and january 2008. our survey was ...

Jun Jia Kai-Kai Wang Xiao-Lin Qin Ya-feng Li, Yong-peng Yuan Yue Xu

The conversion of the cellulose into 5-HMF would experience three steps, cellulose to glycose, glycose to fructose and fructose to 5-HMF. Chloride ion can break down the hydrogen bond in cellucose, chromium can catalyze the isomerization of glycose to fructose, and the high temperature is helpful to cyclohydration of fructose to 5-HMF. In this paper, the sawdust has been directly degraded i...

ژورنال: مجله دندانپزشکی 2002
لطف آذر, مهرداد ,

Papillon Lefevre Syndrome (PLS) is a rare recessive autosomal disease, which is associated with palm and sole hyperkeratosis and early periodontium break down of deciduouse and permanent dentition. In the differential diagnosis of PLS, congenital form of palm and sole hyperkeratosis should be considered.Recently, mutation in catepesin C gene has been recognized as a genetic basis for PLS diseas...

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