Biochemical computing is an emerging field of unconventional computing that attempts to process information with biomolecules and biological objects using Boolean logic. In this work electrode-immobilized glucose-6-phosphate dehydrogenase enzyme catalyzed a reaction which carries out the Boolean AND logic gate. We report the first experimental realization of a sigmoid shape response in one of t...

Motivated by the idea that one day, probably far in the future, the computers and robots will be architectureless, made of collections of numerous ’intelligent’ subsystems or nanomachines able to self-organize each other into computational morphologies with perhaps more computational power than classical electronicbased computers, many studies are burgeoning in different fields (chemistry, biol...

The Annual Bio-Ontologies Meeting has now reached its seventh consecutive year, running as a special interest group (SIG) of the much larger ISMB conference. This year's meeting in Glasgow had approximately 100 attendees. Since the advent of the Gene Ontology, which coincided with the first Bio-Ontologies Meeting, we have seen a year-on-year strengthening of the field; bio-ontologies has moved ...

De novo sequencing and spectral alignment are computationally important for the prediction of new peptides via tandem mass spectrometry (MS/MS). Both approaches are established upon the technique of finding the longest antisymmetric path on formulated graphs. The task is often complicated and the prediction accuracy is compromised when given spectra involve noise data, missing mass peaks, or po...

Molecular logic gates are capable of performing various logic tasks for biomarker detection, disease diagnostics and therapy, and controlling biological progress. Herein, we integrated multiple components of a logic device into a single DNA 3D nano-assembly with a triangular prism structure. Compared with the separate construction of each component in previously reported DNA logic gate systems,...

The measurement of performance of Internet Protocol IP network can be done by Transmission Control Protocol TCP because it guarantees send data from one end of the connection actually gets to the other end and in the same order it was send, otherwise an error is reported. There are several methods to measure the performance of TCP among these methods genetic algorithms, neural network, data min...

We have developed a new halo finding method, Physically Self-Bound (PSB) group finding algorithm, which can efficiently identify halos located even at crowded regions. This method combines two physical criteria such as the tidal radius of a halo and the total energy of each particle to find member particles. No subtle dependence of halo mass functions on various parameters of the PSB method has...

We consider the problem of similarity searches on protein databases based on both sequence and structure information simultaneously. Our program extracts feature vectors from both the sequence and structure components of the proteins. These feature vectors are then combined and indexed using a novel multi-dimensional index structure. For a given query, we employ this index structure to find can...

CURRENT SCIENCE, VOL. 86, NO. 6, 25 MARCH 2004 854 *For correspondence. (e-mail: [email protected]) 13. Akagi, H., Yokozeki, Y., Inagaki, A. and Fujimura, T., Theor. Appl. Genet., 1996, 93, 1071–1077. 14. Akagi, H., Yokozeki, Y., Inagaki, A. and Fujimura, T., Theor. Appl. Genet., 1997, 94, 61–67. 15. Rholf, R. J., NTSYS-PC Version 2.0, Exeter Software, Setauket, New York, 1998. 16. T...

A field study was undertaken during winter (rabi) season of 2013-2014 to explore the effect of graded levels of fertilizers and bio-fertilizers on yield of chickpea, protein content in chickpea seeds and nutrient uptake by the crop. Significantly higher seed and stover yields (1854, 2722 kg ha-1, respectively) were recorded with application of fertilizer @ 100% RDF (25:50:00, kg N:P:K ha-1). Re...