We examined natural water sources in the U.S. for the presence of bacteria resistant to natural and human-produced antimicrobial agents. The impact of these aquatic organisms on diseases in man and animals is unknown but resident bacteria in water represent a potentially important reservoir of resistance genes. Further, the presence of resistant organisms is usually an indication of some select...

microbe-associated molecular patterns (mamps) play key roles as activators of the innate immune response in animals and, analogously, as elicitors of defense responses in plants. however, there are not much investigations concerning their real importance in plant resistance against pathogens. here we used derivatives of flagellin and ef-tu as two well-known mamps against some important fungal a...

Antibiotics are important to successful livestock production. Unfortunately use of antibiotics applies selection pressure that results in antibiotic resistance in exposed populations of bacteria and can also result in antibiotic residues in meat and milk from treated animals. Of major current concern is the risk of transfer of antibiotic resistant bacteria and genes encoding resistance from peo...

Background and Aims: Urinary tract infections are one of the most common human infections seen in all age groups and both sexes. Inappropriate use of antibiotics to treat urinary tract infection causes the resistance of the pathogens to the drug. The present study aimed to determine the frequency of gram-negative and gram-positive bacteria and antibiotic resistance patterns in patients with uri...

Cationic antimicrobial peptides and polymyxins are a group of naturally occurring antibiotics that can also possess immunomodulatory activities. They are considered a new source of antibiotics for treating infections by bacteria that are resistant to conventional antibiotics. Members of the genus Burkholderia, which includes various human pathogens, are inherently resistant to antimicrobial pep...

BACKGROUND Neonatal sepsis is characterised by bacteraemia and clinical symptoms caused by microorganisms and their toxic products. Gram negative bacteria are the commonest causes of neonatal Sepsis. The resistance to the commonly used antibiotics is alarmingly high. The major reason for emerging resistance against antibiotics is that doctors often do not take blood cultures before starting ant...

Bacteria clearly benefit from the possession of an antibiotic resistance gene when the corresponding antibiotic is present. But do resistant bacteria suffer a cost of resistance (i.e., a reduction in fitness) when the antibiotic is absent? If so, then one strategy to control the spread of resistance would be to suspend the use of a particular antibiotic until resistant genotypes declined to low...

Bacteria with intrinsic resistance to antibiotics are found in nature. Such organisms may acquire additional resistance genes from bacteria introduced into soil or water, and the resident bacteria may be the reservoir or source of widespread resistant organisms found in many environments. We isolated antibiotic-resistant bacteria in freshwater samples from 16 U.S. rivers at 22 sites and measure...