the present treatment goals for inflammatory bowel diseases (ibd) especially ulcerative colitis (uc) include rapid induction of clinical remission, steroid-free maintenance of clinical remission, mucosal healing and improvement of quality of life in uc patients. immunomodulators have been reserved for steroid- dependent or steroid- refractory uc patients. among these agents, azathioprine/6-merc...

Rosemary (Rosmarinus officinalis L.) is an evergreen bushy shrub which grows along the Mediterranean Sea, and sub-Himalayan areas. In folk medicine, it has been used as an antispasmodic, mild analgesic, to cure intercostal neuralgia, headaches, migraine, insomnia emotional upset, and depression. Different investigations have highlighted rosemary neuropharmacological properties as their main top...

materials and methods in the present study, a potent nk-producing strain was isolated from cow milk and identified. to enhance the yield of nk, effect of various parameters such as ph, temperature, carbon source, nitrogen source and inoculum size were optimized. strain improvement of p. aeruginosa cmss was done by random uv-mutagenesis. nattokinase was partially purified and the activity was de...

the ideal approach for adequate management of subclinical hyperthyroidism (low levels of thyroid-stimulating hormone [tsh] and normal thyroid hormone level) is a matter of intense debate among endocrinologists. the prevalence of low serum tsh levels ranges between 0.5% in children and 15% in the elderly population. mild subclinical hyperthyroidism is more common than severe subclinical hyperthy...

conclusions a substantial proportion of patients with urethritis sought help from other sources, rather than physicians. the results of our study show that the patients with higher levels of education were more likely to seek help from health care services. it is important to promote the public’s knowledge through informative studies and educational materials in order to encourage patients to s...

Antimicrobial stewardship has been defined as the limitation of inappropriate use of antimicrobials while optimizing the selection, dosing, route, and duration of antimicrobial therapy to maximize clinical cure or prevent infection; limiting unintended consequences, such as emergence of resistance, occurrence of adverse drug events, and selection of pathogenic organisms (such as Clostridium dif...

The Caenorhabditis elegans nuclear RNA interference defective (Nrde) mutants were identified by their inability to silence polycistronic transcripts in enhanced RNAi (Eri) mutant backgrounds. Here, we report additional nrde-3-dependent RNAi phenomena that extend the mechanisms, roles, and functions of nuclear RNAi. We show that nrde-3 mutants are broadly RNAi deficient and that overexpressing N...

Nutraceuticals is a broad term which describes any substance extracted from food sources with additional health benefits along with the basic nutritional value already present in them. They act nonspecifically to promote general well-being of the individuals and also to control and prevent virulent conditions. The term “nutraceutical” combines two words – “nutrient” (a nourishing food component...

BACKGROUND It is increasingly important for decision makers, such as medical and pharmacy managers (or pharmacy therapeutics committee members and staff), to understand the variation and diversity in treatment response as decisions shift from an individual patient perspective to optimizing care for populations of patients. OBJECTIVE To assess the effectiveness of an instructional program on h...

Abstract Background Community hospitals may have challenges implementing core elements of antimicrobial stewardship (ASP) due to lack ID trained pharmacists (PharmD). The COVID-19 pandemic compounded these with constrained resources and staffing. also saw a rise in use (AU) brought forth novel therapeutics, thus increasing the need for robust ASP. We established community ASP rotation PharmD fe...