Taktic, an Amitraz-based insecticide, is commonly used in sub-Saharan Africa to treat cattle for ticks. Due misuse rural dipping pools, some ticks are showing resistance Taktic. This work presents a low-cost e-nose with commercial sensors monitor Taktic levels pool water. The device shows distinctly different measurements the odours of air, distilled water, farm and four insecticide A naive Bay...

common carp, cyprinus carpio (l.) were blood-sampled after 0, 2, 6, 12, 24, 48 and 72 h fasting to find serum baseline levels. there was a significant difference in serum glucose, lactate, triglyceride and total protein but not cholesterol, albumin and calcium levels among the treatments. glucose levels increased with fasting tine and reached to a peak after 6 h. then, the glucose level decreas...

A rapid, sensitive and reproducible HPLC method was developed and validatedfor the analysis of amifostine (AMF) and/or its metabolite, WR-1065 inhuman plasma. The method involves the alkylation of free sulfydryl group with iodoacetic acid followed by derivatization of the drug and its metabolite witho-phthaldialdehyde (OPA) andUVdetection at 340 nm. The derivatized AMF and WR-1065 were eluted i...

Imatinib is an orally administered tyrosine kinase inhibitor which inhibits the Bcr-Abl protein-tyrosine kinase with high selectivity. Imatinib is rapidly absorbed from the gut, after oral intake and has an almost absolute bioavailability of 98%. The metabolism of imatinib is mediated by the cytochrome P450 (CYP) isoenzymes in the liver and gut wall. CGP74588 is a major active metabolite of ima...

Survival of European honey bee (Apis mellifera) colonies has been threatened over the past few decades as Varroa destructor become a growing concern on near-global scale. Prominent treatment methods have included synthetic acaricides amitraz, coumaphos, and tau-fluvalinate. Since widespread resistance to these compounds noted, this study sought investigate V. in Virginia. infestation levels api...

A bioequivalence study of two verapamil formulations (generic verapamil tablets and Isoptin® tablets) was performed by comparing pharmacokinetic parameters of the parent drug and its major metabolite, norverapamil following a single dose administration of 80 mg verapamil hydrochloride in 22 healthy volunteers according to a randomized, two-period, crossover-design study. Moreover, the feasibili...