The study was designed to scientifically evaluate the effect of alchoholic extract of Cyperus rotundus rhizomes, a traditional medicinal herb, on isoproterenol-induce myocardial necrosis in rats model. The albino wistar rats were divided into five different groups with six animal in each group. Group I serves as a control group, group II were given isoproterenol (85 mg/kg s.c) for 2 days while ...

To find out predictive value of elevated liver transaminases as a predictor poor maternal outcome in pregnant women with dengue infection. Our study was retrospective study, conducted tertiary care centre North India from July 1 to December 31, 2021. Data all the infection during above period screened for and fetal outcomes. Elevated who developed DHF, DSS mortality were main measures. Mode del...

Abstract Background Gymnema sylvestre is a reputable medicinal plant commonly explore for the management of diabetes and other ailments in traditional medicine. In present study, we investigated phytochemical compositions effect crude extract, hexane, ethyl-acetate fractions on biochemical hematological parameters Wistar rats . Methods Albino were distributed randomly into control group nine tr...

BACKGROUND & AIMS Blood aspartate aminotransferase (AST) and alanine transaminase (ALT) levels are the most frequently reliable biomarkers of liver injury. Although AST and ALT play central roles in glutamate production as transaminases, peripheral blood levels of AST and ALT have been regarded only as liver injury biomarkers. Glutamate is a principal excitatory neurotransmitter, which affects ...

Transaminases are valuable enzymes for industrial biocatalysis and enable the preparation of optically pure amines. For these transformations they require either an amine donor (amination of ketones) or an amine acceptor (deamination of racemic amines). Herein transaminases are shown to react with aromatic β-fluoroamines, thus leading to simultaneous enantioselective dehalogenation and deaminat...

Eight groups of male Swiss albino mice mice (6 8 weeks old; 23 26g wt) were employed to study the effect of Immunostimulant, (Immunex DS) on the level of abdominal muscle transaminases against Gen Vac B vaccine. In group I, Immunex DS (IDS) was orally administered (@ 150mg/mouse) to 10 mice, in 6 groups of mice (10 in each) IDS was orally administered @ 150mg/mouse on 0 day and Gen Vac B Vaccin...

Abstract Background Telmisartan is a non-peptide angiotensin II receptor antagonist which acts by ACE/AngII/AT1 axis blockade (ARB). In the last years increasing evidence of its metabolic benefits pointed out this drug as most promising ARB for nonalcoholic fatty liver disease (NAFLD) treatment. The aim present study was to investigate effect on treating NAFLD in mice fed with high-fat diet eva...

Introduction Elevated transaminases and/or creatine phosphokinase can indicate underlying muscle disease. Therefore, this study aims to determine the frequency of Duchenne muscular dystrophy/Becker dystrophy (DMD/BMD) in male children and Pompe disease (PD) female with isolated hypertransaminasemia. Methods This multi-center, prospective enrolled patients aged 3–216 months serum alanine transam...