Introduction: Y-DOTATyr3octreotide (Y-DOTATOC) therapy targets tumour cells expressing somatostatin receptors and induces tumour apoptosis and necrosis. However, assessment of treatment response using conventional imaging criteria is unreliable because treatment may induce disease stabilization rather than disease regression, and disease can also be slow to regress despite clinical benefits [1]...

Gallium 67 (67Ga) lung scanning was performed in 100 consecutive cases in which because of the history, clinical data, or abnormal radiological findings, a bronchial carcinoma was suspected. This study allows the conclusion that a negative as well as a positive scan is an important element in the diagnosis of some cases of bronchial carcinoma. The method is most helpful in the preoperative diag...

INTRODUCTION The pathogenicity of late respiratory infections with herpes simplex virus type 1 (HSV-1) in the critically ill is unclear. METHODS In four critically ill patients with persistent pulmonary infiltrates of unknown origin and isolation of HSV-1 from tracheal aspirate or bronchoalveolar lavage fluid, at 7 (1-11) days after start of mechanical ventilatory support, a pulmonary leak in...

This paper is a review of (a) the pathophysiology of the autoimmune deficiency syndrome (AIDS), and (b) the diagnostic procedures nuclear medicine has to evaluate human immunodeficiency virus related disorders. This article is organized in an organ system approach to AIDS pathology. The application of [67Ga]citrate, 111In-labeled white blood cells, [201Tl]chloride, single photon emission comput...

Short treatment courses of ACS have been shown to be of no demonstrable value in the treatment of ARDS. We gave two patients with persistant ARDS a trial of ACS after they demonstrated pulmonary uptake of 67Ga. Brief initial improvement disappeared with tapering of the ACS. A sustained course of ACS led to resolution of the ARDS in both patients. In all, ten patients with established ARDS were ...