This paper presents the object-oriented analysis (OOA) of the on board software of the SACI-1, the firts Brazilian Microsatellite for Scientific Application. Emphasis is put on the object analysis using the OMT (Object Modeling Technique ) as the underlying OOA methodology and employing the best features of a set of others OOA methods. The on board computer (OBC) hardware architecture uses a fa...

United Graduate Schoot qfAgri('ulturai Science, Gijbe U}iiversit.i' rShi:uoka Universit.i'), Gif}i 50i-1i, JcuJan 'Institute.fbr Flermentation, Osaka, 2-17-85 Juso-honnia('hi, ltJtlogaiva-ktt, Osaka 532, Japan "Lahorator.i' qf' Appiied Mic'rohioiogy Detpartment of Appiied Biologicai Chetnistili', RwultJ' qf' Agricutture, Uhiversitr, 836 Ohya, Shi:t`oka 422, Japan Received October 27, 1995 Shi:uoka

Original publication: Laila M. Karlsson and Per Milberg, Seed dormancy pattern and germination preferences of the South African annual Papaver aculeatum, 2007, South African Journal of Botany, (73), 422-428. http://dx.doi.org/10.1016/j.sajb.2007.03.007. Copyright: Elsevier B.V., http://www.elsevier.com/ Postprint available free at: Linköping University E-Press: http://urn.kb.se/resolve?urn=urn:...

The incidence of fungal peritonitis (FP) and the fungi that caused FP were evaluated in 422 patients treated with peritoneal dialysis. During an 11-year period, 804 episodes of peritonitis occurred, 46 (5.7%) of which were caused by fungi. Treatment was successful for 39 patients. Early diagnosis of FP and prompt therapy decreases morbidity and mortality.

The identification and development of a novel series of small molecule Enhancer of Zeste Homologue 2 (EZH2) inhibitors is described. A concise and modular synthesis enabled the rapid development of structure-activity relationships, which led to the identification of 44 as a potent, SAM-competitive inhibitor of EZH2 that dose-dependently decreased global H3K27me3 in KARPAS-422 lymphoma cells.

OBJECTIVES To find out the frequency of Alzheimer's and Vascular dementia in the elderly patients. METHODS This cross sectional descriptive study was conducted in Department of Medicine, Ziauddin Hospital Karachi from 1st October 2013 to 31st March 2014. Patients with symptoms of dementia for more than 6 months duration, and Mini Mental State Examination score <24 were included in this study....

PURPOSE N-chlorotaurine (NCT) and its analogues N-monochloro-2,2-dimethyltaurine (NVC-612) and N-dichloro-2,2-dimethyltaurine (NVC-422) are new anti-infectives for topical treatment for conjunctivitis. The aim of this study was to show that these compounds are safe in an EpiOcular model and effective in corneas infected ex vivo. METHODS Corneal buttons were excised from porcine eyes. In 183 o...

Quantitative structure pharmacokinetic relationship (QSPKR) modeling can be used to predict the biliary clearance and percentage of dose eliminated in bile (PDb) in humans before clinical studies. Recently, a QSPKR model based on in-house compounds was derived using simple physicochemical descriptors to predict the PDb in rats (Drug Metab Dispos 38:422–430, 2010). Our objective was to evaluate ...

Quantitative structure pharmacokinetic relationship (QSPKR) modeling can be used to predict the biliary clearance and percentage of dose eliminated in bile (PDb) in humans before clinical studies. Recently, a QSPKR model based on in-house compounds was derived using simple physicochemical descriptors to predict the PDb in rats (Drug Metab Dispos 38:422–430, 2010). Our objective was to evaluate ...