In order to elucidate whether or not the spectral and circular dichroic changes observed during the biodegradative threonine deaminase reaction are caused by the Schiff base formation between the enzyme-bound pyridoxal phosphate and the dehydrated intermediate, the role of substituents and the absolute configuration of the 0 carbon of substrates was investigated using various analogs of L-threo...

Controversy exists concerning the most accurate method for defining diastolic blood pressure in pregnancy. Both disappearance (phase V) and muffling (phase IV) of Korotkoff sounds have been advocated. We previously reported an objective noninvasive method for measuring blood pressure, called K2 analysis, which in nonpregnant subjects was not different from intra-arterial diastolic blood pressur...

A microphysiometer was used to quantify the rate of extracellular acidification by C6 glioma cells and L fibroblasts expressing recombinant dopamine D2 receptors. The dopamine D2 receptor agonist, quinpirole, accelerated the rate of acidification of the medium by C6 cells expressing either the short or long form of D2 receptors, D2(415) and D2(444), but not by wild-type cells that were not tran...

INTRODUCTION This study aimed to estimate the prevalence of Neisseria gonorrhoeae and Chlamydia trachomatis infections and to assess the therapeutic management of vaginal/urethral discharge and dysuria in patients with human immunodeficiency virus in Luanda, Angola, taking into account World Health Organization recommendations for sexually transmitted infection syndromic management. METHODOLO...

Dear Sir, The national needs for blood in Greece exceed 600,000 units annually (approximately 50 units per 1,000 inhabitants). The large number of transfusiondependent thalassaemia patients, car accident victims and poor implementation of "patient blood management" are the main reasons why Greeks exceed the European average of 40 donations/1,000 inhabitants needed to cover national needs. Despi...

airway and is the most common chronic disease in children characterized by wheezing. Wheezing may occur even once it is up to 50% of all infants and children under 3 years old and topic dermatitis affecting over 10% of children. Objective: To define incidence and prevalence of asthma and others allergic diseases in population of less than 5 years of age in Juarez Hospital Mexico. Results: We ev...

BACKGROUND Adenosquamous carcinoma of the pancreas is rare. Our understanding of the disease and its prognosis comes mainly from small retrospective studies. METHODS Using the Surveillance, Epidemiology, and End Results (SEER) database (1988 to 2007), we identified patients with adenosquamous carcinoma (n = 415) or adenocarcinoma (n = 45,693) of the pancreas. The demographics, tumor character...