نتایج جستجو برای: 3 d pyrimidines
تعداد نتایج: 2219499 فیلتر نتایج به سال:
The chemical changes occurring during embryonic development have been studied by several workers (l-3). In the hen’s egg there is very little nucleic acid present, whereas a considerable synthesis of both desoxypentose nucleic acid (DNA) and ribose nucleic acid (RNA) occurs in the embryo (4-6). Recently, methods for the determination of purines and pyrimidines in small amounts of tissue have be...
A series of 4-amino-6-benzimidazole-pyrimidines was designed to target lymphocyte-specific tyrosine kinase (Lck), a member of the Src kinase family. Highly efficient parallel syntheses were devised to prepare analogues for SAR studies. A number of these 4-amino-6-benzimidazole-pyrimidines exhibited single-digit nanomolar IC(50)s against Lck in biochemical and cellular assays. These 4-amino-6-be...
In the present study, a series of benzothiazol derivatives 3a-l containing pyrazolo[3,4-d]pyrimidine moiety at the second position were synthesized and characterized by analytical and spectral data. The compounds were tested for their in vitro antimicrobial activity. Compounds 1-(1,3-benzothiazol-2- yl)-3-methyl-4-phenyl-1H-pyrazolo[3,4-d]pyrimidine (3a), 1- (1,3-benzothiazol-2-yl)-4-(4-chlorop...
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