نتایج جستجو برای: 04 calcium

تعداد نتایج: 196284  

2013
V. Wallace McCarlie James K. Hartsfield Janice S. Blum Carlos González-Cabezas Judith R. Chin George J. Eckert Lorri A. Morford Mark D. Pescovitz Henry Rodriguez Margherita Fontana Richard L. Gregory

Bacterial adherence to the acquired dental pellicle, important in dental caries (caries), is mediated by receptor-adhesins such as salivary agglutinin binding to Streptococcus mutans antigen I/II (I/II). Ten selected I/II epitopes were chosen to determine their reactivity to human salivary IgA. Previous studies suggested that a specific HLA biomarker group (HLA-DRB1*04) may have differential in...

Journal: :JAMA 1995
B M Psaty S R Heckbert T D Koepsell D S Siscovick T E Raghunathan N S Weiss F R Rosendaal R N Lemaitre N L Smith P W Wahl

OBJECTIVE To assess the association between first myocardial infarction and the use of antihypertensive agents. DESIGN AND SETTING We conducted a population-based case-control study among enrollees of the Group Health Cooperative of Puget Sound (GHC). PATIENTS AND METHODS Cases were hypertensive patients who sustained a first fatal or nonfatal myocardial infarction from 1986 through 1993 am...

2013
Lei Wang Jianjun Chang Diana Varghese Michael Dellinger Subodh Kumar Anne M. Best Julio Ruiz Richard Bruick Samuel Peña-Llopis Junjie Xu David J. Babinski Doug E. Frantz Rolf A. Brekken Amy M. Quinn Anton Simeonov Johnny Easmon Elisabeth D. Martinez

The pharmacological inhibition of general transcriptional regulators has the potential to block growth through targeting multiple tumorigenic signalling pathways simultaneously. Here, using an innovative cell-based screen, we identify a structurally unique small molecule (named JIB-04) that specifically inhibits the activity of the Jumonji family of histone demethylases in vitro, in cancer cell...

2009
Fan Jiang Alan J. Husband Gregory J. Dusting

Isoflavones have been suggested to have hypolipidemic effects. As these compounds undergo complex metabolism in the body, the biological actions of isoflavone metabolites are largely unknown. We studied the hypolipidemic effects of two isoflavone metabolites initially identified in the human urine, cis-tetrahydrodaidzein (NV-04) and transtetrahydrodaidzein (NV-05) in apolipoprotein(E)-deficient...

2010
Melinda Paizs László Siklós József I. Engelhardt

Motor neurons that exhibit differences in vulnerability to degeneration have been identified in motor neuron disease and in its animal models. The oculomotor andhypoglossal neurons are regarded as the prototypes of the resistant and susceptible cell types, respectively.Because an increase in the level of intracellular calciumhas been proposed as a feature amplifying degenerative...

2017
Kuo-Liang Yang Zheng-Zhong Zheng

OBJECTIVE Human leukocyte antigen (HLA) DRB1*04:36 is a low-frequency HLA-DRB1 allele. The aim here is to report the ethnicity of DRB1*04:36 and its associated HLA haplotypes among Taiwanese individuals. MATERIALS AND METHODS A sequence-based typing method was employed to confirm this low incidence allele. Polymerase chain reaction was performed to amplify exons 2 and 3 of the HLA-A and HLA-B...

2008
I. Radinschi

We obtain the energy distribution of a Schwarzschild black hole in a magnetic universe in the Tolman prescription. PACS: 04. 20.-q; 04. 70.-s

2011
Lorena Citterio Marco Simonini Laura Zagato Erika Salvi Simona Delli Carpini Chiara Lanzani Elisabetta Messaggio Nunzia Casamassima Francesca Frau Francesca D'Avila Daniele Cusi Cristina Barlassina Paolo Manunta

The importance of excess salt intake in the pathogenesis of hypertension is widely recognized. Blood pressure is controlled primarily by salt and water balance because of the infinite gain property of the kidney to rapidly eliminate excess fluid and salt. Up to fifty percent of patients with essential hypertension are salt-sensitive, as manifested by a rise in blood pressure with salt loading. ...

1989
A. L. OBAID

Extrinsic absorption changes exhibited by potentiometric dyes have established the ionic basis of the action potential in synchronously activated populations of nerve terminals in the intact neurohypophyses of amphibia and mammals (Salzberg et al., 1983; Obaid et al., 1983, 1985b). Also, large and rapid changes in light scattering, measured as transparency, have been shown to follow membrane de...

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