Although vesicular trafficking is essential for a large variety of cellular processes, the regulation of vesicular trafficking is still poorly understood. Members of the Rho family of small GTPases have recently emerged as important control elements of many stages of vesicular trafficking, providing new insight into the regulation of these events. We will discuss the diverse roles played by Rho...

2. Escobar A. The pathology of neurocysticercosis. In cysticercosis of Central nervous system. Placio E Robriguez Carabasal I, Taveras J (eds). Spring field IL; CC Thomas, 1983;27-54. Fig. 2 : MRI brain sagittal section hypointense T1 image showing multiple vesicular stage neurocysticercosis Fig. 1 : MRI brain transverse section hypointense T1 image showing multiple vesicular stage neurocystice...

Brown alga, Turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). The extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. Minimal inhibitory concentration was determined for active extracts by broth dilution method. The antiviral activity and cytotoxicity of the extracts were tested in human embryon...

The endocytosis of horseradish peroxidase (HRP) by the vascular cells of retinal and choroidal blood vessels was compared in immersion and perfusion fixed eyes from individual rats. The mechanisms of endocytosis of HRP appeared identical in both retinal and choroidal vessels. The bulk of internalised tracer occurred in macropinosomes 300-400 nm in diameter. Tracer was localised to a 20-30 nm la...

The present study was designed for the development of a stable sustained release liposomal drug delivery system for tamoxifen citrate (TC) using soya phosphatidylcholine (SPC), cholesterol (CH) and span 20 as main ingredients. Liposomes were prepared by formation of thin lipid film followed by hydration. The mean vesicle diameter was found to be 203.5 Â 19.5 nm with 21% of the liposomal populat...

Developing oocytes of the cnidarian Bunodosoma cavernata are located within the mesoglea of the mesenteries of the gastrovascular cavity. The cortex of the more mature vitellogenic oocytes contains numerous, electron-dense, membrane-bound, cortical granules. The surface of these oocytes possesses prominent radially projecting structures termed cytospines. Each cytospine has a core of microfilam...

The structure and composition of lipoprotein fractions from two patients with fish eye disease were examined. The composition of very low density lipoproteins (VLDL) was normal, although total mass was greatly elevated. The mean particle sizes of the VLDL were 44.6 +/- 22.2 and 42.8 +/- 19.8 nm for Patients 1 and 2, respectively. Intermediate density lipoprotein (IDL) concentrations in patients...

Sarcoplasmic vesicles and beta-glycogen particles 30-40 mmicro in diameter were isolated from perfused rabbit skeletal muscle by the differential precipitation-centrifugation method. This microsomal fraction was subjected to zonal centrifugation on buffered sucrose gradients, in a B XIV Anderson type rotor, for 15 hr at 45,000 rpm in order to separate the two cytoplasmic organelles. Zonal profi...

Intravascular platelet aggregation induced by ADP injection into the carotid artery of rabbits caused ipsilateral cerebrovascular injuries. We have observed the details of these in vivo vascular changes under the electron microscope. Intracytoplasmic vacuole (1.0-2.0 micron in diameter) formation and partial deendothelialization followed by platelet thrombus formation were characteristic change...