Paracoccidioidomycosis presenting as a sarcoid-like plaque may be misdiagnosed as leprosy, especially when shared endemic areas are concerned. We report the case of a Brazilian male patient presenting with an ulcerated plaque on his left ear and neighboring areas. The plaque simulated tuberculoid leprosy type 1 reaction, both clinically and histopathologically. A perineural granuloma with no or...

Oft-cited as a deterrent to elimination of the disease, stigma is still a critical feature of the leprosy landscape leading to ostracism, loss of employment, loss of housing, ridicule and rejection from society. The reason for leprosy-stigma rests historically and culturally on the mythology about the disease's origin and transmission, and its aesthetic features such as the enigmatic physical d...

BACKGROUND although the foci of leprosy once present in Spain are now under control and almost inactive, isolated cases are still occasionally diagnosed. Meanwhile, population migration has brought about an increase in the incidence of cases corresponding to individuals from countries where leprosy is endemic, leading to changes in the epidemiology of this disease. OBJECTIVES the aim of this ...

Aware of the world-wide concern about the dapsone monotherapy problem, the National TB-Leprosy Programme (NTLP) has gradually introduced the multiple drug (MDT) treatment of leprosy in its activities . The programme as most of the delegates will recall started in July 1 977, and 3 years later MDT was started in some patients thought to be resistant to dapsone . Since then, the number of patient...

Scalp is considered to be one of the ' immune zones' in leprosy. The involvement of the scalp in leprosy has been reported, though rarely. In the cases reported so far, the scalp was found to be affected mainly in bacilliferous leprosy and the involvement was mostly on the bald area of the scalp . However, in the present case a tuberculoid lesion was found on the hairy occipital area of the sca...

for publication on June 2, 2005. 2 T. Narang, M.D.; S. Dogra, M.D., D.N.B., M.N.A.M.S.; and I. Kaur, M.D., M.N.A.M.S., Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Reprint requests to: Dr. Inderjeet Kaur, Additional Professor, Dept. of Dermatology, Venereology and Leprology, PGIMER, Chandigarh-160 012, India; ...

We have searched for Mycobacterium leprae DNA for 36kDa protein in urine using a M. leprae specific PCR technique. A limited number of 16 patients (of which 11 belonged to lepromatous leprosy and five to tuberculoid leprosy) and eight healthy individuals were included for the present study. The number of urine samples positive by PCR were 36.4% (4/11) in lepromatous patients and 40% (2/5) in tu...

Histoid leprosy is extremely rare in children. Molluscum contagiosum-like lesions in the setting of histoid leprosy is a highly atypical presentation and may signify the process of "transepidermal elimination" in lesions with high bacillary load. A case of histoid leprosy with umbilicated papules and nodules mimicking molluscum contagiosum is reported in a 10-year-old Indian boy.

In his study of the immunological. relations between leprosy and tuberculosis, Floch (1) performed von Pirquet and Mitsuda tests on 128 children of the Marchoux School and of the B. de Cayena Dispensary. Their ages varied from 6 to 14 years. Forty-three of them suffered from tuberculoid leprosy, while 85 had the indeterminate form. In carrying out the Mitsuda test Floch used as his antigen, not...

The diagnosis of leprosy continues to be based on clinical symptoms and early diagnosis and treatment are critical to preventing disability and transmission. Sensitive and specific laboratory tests are not available for diagnosing leprosy. Despite the limited applicability of anti-phenolic glycolipid-I (PGL-I) serology for diagnosis, it has been suggested as an additional tool to classify lepro...