BACKGROUND AND PURPOSE This paper evaluated the effect of acute homocysteine administration on inflammatory cytokine tumor necrosis factor-alpha (TNF-α) expression and neuronal apoptosis in the rat hippocampus and investigated the effects of vitamin C treatment on homocysteine-induced inflammation and neuronal death. METHODS Subjects were three-week-old, male Sprague-Dawley rats. Rats for the...

Nutritional rickets has occasionally been described in children with lamellar ichthyosis, but their vitamin D endocrine status has not been described. We report 3 cases of vitamin D-deficiency rickets associated with ichthyosis in African children. A 13-month-old Nigerian boy with lamellar ichthyosis had rib beading, elevated alkaline phosphatase, and rachitic changes on radiographs. His ricket...

the objective of this study was to evaluate quality of frozen-thawed bull semen processed with extenders containing vitamin c and e as antioxidants. pooled semen's were collected from 5 bulls and diluted to a concentration of 30 × 106 sperm/ml with citrate –egg yolk (cey) or tris – egg yolk (tey) extenders. the diluted semen was divided to 5 aliquots including control and 4 experimental groups....

Vit i l igo i s an acquired depigmentat ion disorder of the skin in which there is loss of epidermal melanocytes. The prevalence of vitiligo is approximately 0.1-2% worldwide. The precise pathogenesis of vitiligo remains subtle and is probably multifactorial 1. Treatment of vitiligo remains an interesting topic and many centers have been reported as having varying degrees of success. Medical th...

objective: critical macromolecules such as dna maybe damaged by free radicals that are generated from the interaction of ionizing radiation with biological systems. melatonin and vitamin c have been shown to be direct free radical scavengers. the aim of this study was to investigate the in vivo/in vitro radioprotective effects of melatonin and vitamin c separately and combined against genotoxic...

Alopecia areata (AA) is an inflammatory hair loss of unknown etiology. AA is chronic and relapsing, and no effective cure or preventive treatment has been established. Vitamin D was recently reported to be important in cutaneous immune modulation as well as calcium regulation and bone metabolism. It is well known that areata is common clinical finding in patients with vitamin D deficiency, vita...

INTRODUCTION The ethiopathogenesis of tympanosclerosis has not been completely under- stood yet. Recent studies have shown that free oxygen radicals are important in the formation of tympanosclerosis. Melatonin and Vitamin C are known to be a powerful antioxidant, interacts directly with Reactive Oxygen Species and controls free radical-mediated tissue damage. OBJECTIVE To demonstrate the pos...

background: ascorbic acid (vitamin c) is one of the most commonly water soluble vitamins. extra energy is necessary for the exercise is not often attributed to intake of vitamin c, long-term and intense exercise can lead to oxidative damage to cellular compounds and also contribute to muscle fatigue and decrease exercise performance. limited data are available regarding to the efficacy of vitam...

OBJECTIVE The aim of the liposoluble vitamin solution in the DBM formulation is to enhance the biovailability, the stability, the half-life and the therapeutic efficacy of the components without resorting to excessive or toxic doses. METHOD The DBM vitamin solution contains 0.5 grams of vitamin A palmitate ester, 0.5 grams of all-trans-retinoic acid (ATRA), and 2 grams of β-Carotene, in 1 000...