نتایج جستجو برای: subcutaneous human adipocyte

تعداد نتایج: 1676266  

2012
Nigel Hoggard Morven Cruickshank

Objective: We have recently identified secretory leukocyte peptidase inhibitor (SLPI), a component of the innate host defence in human omental adipose tissue. The objective of this study was to determine if the SLPI secreted by adipose tissue is regulated by changes in obesity. Materials/Methods: Circulating SLPI was measured in lean/overweight (n = 13), obese (n = 10) and obese diabetic (n = 1...

Journal: :Diabetes 2008
Séverine Ledoux Isabelle Queguiner Simon Msika Sophie Calderari Pierre Rufat Jean-Marie Gasc Pierre Corvol Etienne Larger

OBJECTIVE The expansion of adipose tissue is linked to the development of its vasculature. However, the regulation of adipose tissue angiogenesis in humans has not been extensively studied. Our aim was to compare the angiogenesis associated with subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) from the same obese patients in an in vivo model. RESEARCH DESIGN AND METHODS Adi...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2009
Kaiying Guo Jonathan Mogen Samuel Struzzi Yiying Zhang

Leptin has profound effects on adipose tissue metabolism. However, it remains unclear whether direct leptin signaling in adipocytes is involved. We addressed this question by transplanting inguinal adipose tissue stromal vascular cells (SVCs) from 4- to 5-wk-old wild-type (WT) and leptin receptor-deficient [Lepr(db/db) (db)] mice to inguinal and sternal subcutaneous sites in Ncr nude mice. Both...

Journal: :Diabetes 2002
Vanessa van Harmelen Andrea Dicker Mikael Rydén Hans Hauner Fredrik Lönnqvist Erik Näslund Peter Arner

Site differences in adipose tissue function may have implications for insulin-resistant conditions. In mature adipose tissue, subcutaneous adipocytes have higher leptin secretion, similar tumor necrosis factor (TNF)-alpha secretion, and lower catecholamine-stimulated lipolysis as compared with omental adipocytes. In this study, lipolysis and leptin and TNF-alpha secretion were compared between ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید