Among critically ill patients, acute kidney injury (AKI) is a relatively common complication that is associated with an increased risk for death and other complications. To date, no treatment has been developed to prevent or attenuate established AKI. Dialysis often is required, but the optimal timing of initiation of dialysis is unknown. Data from the Program to Improve Care in Acute Renal Dis...

Renal dysfunction (RD) and venous congestion are related and common in heart failure (HF). Studies suggest that venous congestion may be the primary driver of RD in HF. In this study, we sought to investigate retrospectively the relationship between common measures of renal function with caval congestion and mortality among outpatients with HF and RD. We reviewed data from 103 HF outpatients (4...

BACKGROUND Dehydration is a frequent clinical problem. No single laboratory value has been found to be accurate; however, the BUN/Creatinine Ratio appears the most sensitive parameter. The respiratory variation (Caval Index, CIn) in the diameter of the inferior vena cava has been investigated as a non-invasive marker for the intravascular volume status. AIM The present study is performed with...

What is the longest rope on the unit sphere? Intuition tells us that the answer to this packing problem depends on the rope’s thickness. For a countably infinite number of prescribed thickness values we construct and classify all solution curves. The simplest ones are similar to the seamlines of a tennis ball, others exhibit a striking resemblance to Turing patterns in chemistry, or to ordered ...

Abstract Introduction Renal dysfunction is one of the most important comorbidities in patients with chronic heart failure (HF) and frequently accentuated setting acute HF (AHF). Serum creatinine blood urea nitrogen (BUN) have been classically used as markers renal dysfunction, despite having several limitations. High (BUN)/creatinine ratio has associated higher mortality HF. We aimed to predict...

objective(s):bradykinin is a part of the kinin-kallikreinsystem which is involved in ischemia-reperfusion injury via b1 and b2 receptors.noscapine is a non-competitive antagonist of bradykinin receptors. noscapine has been reported to to be able to protect some organs against ischemia-reperfusion injury but its effect on renal ischemia-reperfusion injury (rir) in rats is unknown. therefore, the...