OBJECTIVES Selective serotonin reuptake inhibitor (SSRI) prescriptions for children and adolescents have increased greatly in recent years despite a paucity of demonstrated safety and efficacy data and a lack of clear guidelines for use. Our study sought to describe family physician and pediatrician SSRI prescribing patterns for children and adolescents, identify influences on SSRI prescription...

Anxiety and depression are very common during pregnancy. Post-partum period may frequently be complicated by more pro found due to hormonal changes, which lead fatal consequences for both — the mother child. The most commonly prescribed group of drugs ambulatory patient care is selective serotonine reuptake inhibitors (SSRIs). Absence clinical trials where pregnant or breast-feeding women were ...

Inadequate treatment response and emotional blunting are common challenges with selective serotonin reuptake inhibitors/serotonin-noradrenaline inhibitors (SSRIs/SNRIs) for major depressive disorder (MDD). We investigated the effectiveness of vortioxetine on in patients partial to SSRIs/SNRIs. Patients MDD who experienced a SSRI/SNRI monotherapy at adequate dose ?6 weeks were switched 8 10-20 m...

to the editor: Several publications have recently reported an association between maternal treatment with selective serotonin-reuptake inhibitors (SSRIs) late in pregnancy and adverse outcomes in infants. These outcomes have included persistent pulmonary hypertension of the newborn (PPHN), as reported by Chambers et al. (Feb. 9 issue),1 and the neonatal abstinence syndrome, a condition found in...