Three patients had hypertrophic obstructive cardiomyopathy and coronary artery spasm. The clinical diagnosis of hypertrophic obstructive cardiomyopathy, in all patients, was confirmed by echocardiography and angiography. Significant spasm of the right coronary artery was demonstrated in each patient by selective coronary arteriography. One patient had atherosclerotic obstructive three vessel di...

Coronary arteriography was performed before and after the intracoronary injection of nitroglycerin to determine the presence or absence of spasm in patients within the first 12 hours of acute myocardial infarction. Coronary arterial spasm was demonstrated in six of fifteen (40%) acute myocardial infarctions associated with coronary artery disease. In five of the six instances the interval from ...

We report a 67-year-old Japanese man who presented with worsening heart failure with asymptomatically transient ischemic ST-segment depression. Left ventriculography showed diffuse hypokinesis; asymptomatic coronary artery spasm was evoked by the acetylcholine provocation test. Endomyocardial biopsy exhibited hypertrophic cardiomyocytes and scattered microscopic focal myocardial necrosis with a...

Nine cases of hemifacial spasm have been treated by posterior fossa exploration without mortality or significant morbidity. In only three was definite pathology found, but the hemifacial spasm was abolished in eight patients and markedly diminished in the remaining patient. The condition has reccurred in one patient. Microsurgical techniques make the operation safe and accurate. We suggest that...

Coronary artery spasm is a recognized cause of myocardial infarction. This report describes a case of myocardial infarction attributed to pure coronary spasm which was halted by a double perfusion with streptokinase and nitroglycerin. Further coronary artery spasm leading to a myocardial infarction could not be avoided several weeks later, although the patient was left on calcium channel blocke...

Diffuse esophageal spasm is a rare motility disorder. The primary symptoms include dysphagia, and chest pain. There is array of treatments available from medical therapy with nitrates to surgical therapy; Heller myotomy. We present a case of severe Diffuse Esophageal Spasm (DES) that showed one of the highest Distal Contractile Integral (DCI) per manometry. Patient was treated with Botulinum To...

1. In specimens of freshly hatched squid, Loligo pealii, nicotine acts upon the cerebral ganglia alone. 2. After 1 minute in the nicotine solution 1:500,000, the latent period for the mantle spasm is independent of the time spent in the solution. 3. The mantle spasm is conditioned by a chemical reaction, since the temperature coefficient of the process has a magnitude of about 2.8. 4. The veloc...

Osgood (1889) is generally credited with the introduction of the term " diffuse spasm " of the oesophagus. However, though Moersch and Camp (1934) recorded a classical description of the clinical and radiological features of the disease it attracted little interest until the introduction of oesophageal motility studies in the 1950s. Since then a characteristic motility pattern has been describe...