نتایج جستجو برای: serotonin 5ht2a receptor

تعداد نتایج: 614261  

Journal: :Hamostaseologie 2009
D Duerschmied C Bode

Serotonin is transported by platelets and released upon activation. This induces constriction of injured blood vessels and enhances platelet aggregation to minimize blood loss. Consequently, serotonin receptor antagonists have been tested for their anti-ischemic potency in atherothrombotic disease. Unfortunately, the results have been contradictory. Recent murine studies found that activation o...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1982
A Biegon B S McEwen

Estrogens were found to exert a biphasic effect on the density of serotonin receptors in the female rat brain: an acute reduction in serotonin receptor density throughout the brain is followed 48 to 72 hr later by a selective increase in those brain regions known to contain estrogen receptors--hypothalamus, preoptic area, and amygdala. The acute reduction in serotonin receptor density can be mi...

Journal: :Synapse 2004
Jordi Serrats Andreu Raurich M Teresa Vilaró Guadalupe Mengod Roser Cortés

We used double-label in situ hybridization to examine the cellular localization of 5-ht(5B) receptor mRNA in relation to serotonin transporter mRNA in the rat dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). 5-ht(5B) receptor mRNA hybridization signal was often found on serotonin transporter mRNA-positive neuron profiles. The degree of cellular colocalization of these ...

Journal: :Journal of neurodevelopmental cognition 2022

Treatment developments, brain imaging studies, and results of pharmacological research elicit revision related pathological theories to Obsessive-compulsive disorder (OCD) new patterns. One the important alluring patterns under neurobiological approach corresponding pathology treatment obsessive-compulsive is animal models which are used in this disorder. Insomuch, many endeavors have been appl...

2009
Stéphane Doly Jesus Bertran-Gonzalez Jacques Callebert Alexandra Bruneau Sophie Marie Banas Arnauld Belmer Katia Boutourlinsky Denis Hervé Jean-Marie Launay Luc Maroteaux

The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) reverses dopamine and serotonin transporters to produce efflux of dopamine and serotonin, respectively, in regions of the brain that have been implicated in reward. However, the role of serotonin/dopamine interactions in the behavioral effects of MDMA remains unclear. We previously showed that MDMA-induced locomotion, ...

Journal: :Hepatology 1998
S Balasubramanian C S Paulose

The involvement of serotonin and its receptor subtype in the induction of hepatocyte DNA synthesis was investigated in primary cultures of adult rat hepatocytes. Serotonin caused a dose-dependent increase in DNA synthesis in primary cultures of rat hepatocytes in the presence of epidermal growth factor (EGF) and insulin, as measured by [3H]thymidine incorporation. The serotonin S2 receptor anta...

Journal: :Biochemistry 2004
Thomas J Pucadyil Shanti Kalipatnapu Kaleeckal G Harikumar Nandini Rangaraj Sadashiva S Karnik Amitabha Chattopadhyay

Serotonergic signaling appears to play a key role in the generation and modulation of various cognitive, behavioral, and developmental processes. The serotonin(1A) receptor is an important member of the superfamily of seven transmembrane domain G-protein-coupled receptors and is the most extensively studied among the serotonin receptors. Several aspects of serotonin(1A) receptor biology such as...

Journal: :The Journal of experimental biology 2008
Sabeen Mapara Shawn Parries Caitlin Quarrington Kee-Chan Ahn Warren J Gallin Jeffrey I Goldberg

Helisoma trivolvis has served as a model system to study the functions of serotonin (5-HT) from cellular, developmental, physiological and behavioural perspectives. To further explore the serotonin system at the molecular level, and to provide experimental knockout tools for future studies, in this study we identified serotonin receptor genes from the H. trivolvis genome, and characterized the ...

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