OBJECTIVE To study whether formal education and occupational class are associated with incidence of rheumatoid arthritis overall and with the incidence of the two major subgroups of rheumatoid arthritis-seropositive (RF+) and seronegative (RF-) disease. METHODS 930 cases and 1126 controls participated in a population based case-control study using incident cases of rheumatoid arthritis, carri...

BACKGROUND Levels of pentosidine (representative of advanced glycation end-products) in sera of patients with rheumatoid arthritis are increased when compared with sera of other diagnoses or healthy controls. These levels have been reported to correlate with clinical indices of rheumatoid arthritis activity and with laboratory markers of inflammation. The purpose of this study was to find out i...

Rheumatoid arthritis, a systemic inflammatory disease, may induce pulmonary manifestations. We describe a case of longstanding RA presenting with eosinophilic pneumonia. Rare case reports of tissue eosinophilia involving isolated organs in the setting of rheumatoid arthritis exist in the literature. It has been shown that the production of proinflammatory cytokines activates different cell grou...

background: osteoporosis (op) is a common complication of inflammatory arthritis such as rheumatoid arthritis (ra). in this study we evaluated osteoporosis and its related factors in ra patients. methods: this cross - sectional study was carried out from 2010 to 2011 on 121 women with ra aged 45-75 years. these patients were selected and divided in two groups according to their bone mineral den...

background: antiphospholipid antibody syndrome (aps) can either occur as a primary syndrome or associated with other autoimmune diseases such as systemic lupus erythematosus (sle). anticardiolipin antibody (acl) of igg and/or igm isotype in blood, measured by a standardized elisa is the most acceptable laboratory criteria. aps igg isotype, particularly igg2 subclass is more strongly associated ...

this cross-sectional study is conducted to determine the prevalence of asymptomatic cervical spine subluxation in rheumatoid arthritis patients by plain radiographs and its relation to demographic and clinical characteristics, disease activity measures and medications. 100 rheumatoid arthritis patients (18 male and 82 female) were selected randomly, according to the american college of rheumato...

background and objectives: mycoplasma arthritidis mitogen (mam) superantigen has been shown to induce chronic arthritis, which resembles human rheumatoid arthritis (ra) in a rodent model. however, its role as a causative agent in human ra is not well understood yet. the aim of this study was to investigate the presence of mam superantigen gene in the synovial fluid (sf) of ra patients. material...

background: rheumatoid arthritis (ra) is an autoimmune systemic disease. most common autoimmune diseases are multisystem disorders that may also present with otological manifestations, and autoimmune inner ear disease accompanied by vestibular dysfunction. this study aimed to compare the vestibular function between ra patients and normal subjects using cervical vestibular evoked myogenic potent...

Sera from 53 Nigerian patients satisfying the American Rheumatism Association criteria for a diagnosis of definite or probable rheumatoid arthritis and sera from sick and healthy Nigerian controls were tested for rheumatoid factor, autoantibodies, and immunoglobulin levels. Rheumatoid factor and autoantibodies were found no more frequently in patients with rheumatoid arthritis than in controls....