نتایج جستجو برای: redox status

تعداد نتایج: 450149  

Journal: :Clinical and Experimental Immunology 2004

Journal: :Circulation research 2004
Daniel A Brenner Mohit Jain David R Pimentel Bo Wang Lawreen H Connors Martha Skinner Carl S Apstein Ronglih Liao

Primary amyloidosis is a systemic disorder characterized by the clonal production and tissue deposition of immunoglobulin light chain (LC) proteins. Congestive heart failure remains the greatest cause of death in primary amyloidosis, due to the development of a rapidly progressive amyloid cardiomyopathy. Amyloid cardiomyopathy is largely unresponsive to current heart failure therapies, and is a...

2013
Richard E. Frye Stepan Melnyk George Fuchs Tyra Reid Stefanie Jernigan Oleksandra Pavliv Amanda Hubanks David W. Gaylor Laura Walters S. Jill James

Treatments targeting metabolic abnormalities in children with autism are limited. Previously we reported that a nutritional treatment significantly improved glutathione metabolism in children with autistic disorder. In this study we evaluated changes in adaptive behaviors in this cohort and determined whether such changes are related to changes in glutathione metabolism. Thirty-seven children d...

Journal: :Journal of neuroscience research 2001
Y W Lee B Hennig J Yao M Toborek

Cellular and molecular mechanisms of methamphetamine (METH)-induced neurotoxicity may involve alterations of cellular redox status and induction of inflammatory genes in endothelial cells. To study these hypotheses, molecular signaling pathways of METH-induced inflammatory responses via activation of redox-sensitive transcription factors were investigated in human brain microvascular endothelia...

Journal: :The Journal of pharmacology and experimental therapeutics 2005
Subrata Chakrabarti Olga Vitseva David Iyu Sonia Varghese Jane E Freedman

Platelet and vascular stimulation leads to release of reactive oxygen species (ROS) that are known to influence vascular reactivity and thrombosis. Dipyridamole is a vasodilator and platelet inhibitor that has previously been shown to have direct antioxidant properties. The antioxidant effects of dipyridamole on vascular cell-derived ROS are not known; therefore, dipyridamole was incubated with...

Journal: :Biochemical and Biophysical Research Communications 2010

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