Vertebral osteomyelitis (VO) is a rare, slowly progressing disease that often causes neuromuscular complications. Epidural block non-surgical treatment used in patients with radicular pain to deliver drugs the epidural space; it generally known be safe method, but can occasionally cause infection. Herein, we present rare case of VO severe complications developed patient who underwent lumbar tra...

The blood-spinal cord barrier (BSCB) is the functional equivalent of the blood-brain barrier (BBB) in the sense of providing a specialized microenvironment for the cellular constituents of the spinal cord. Even if intuitively the BSCB could be considered as the morphological extension of the BBB into the spinal cord, evidence suggests that this is not so. The BSCB shares the same principal buil...

Transcutaneous electrical stimulation of the central nervous system was used to measure motor conduction velocity in the human spinal cord in 21 subjects aged 22 to 75 years (mean 55 years), none of whom had neurological disease. The motor conduction velocity between the sixth cervical (C6) and first lumbar (L1) vertebral levels was 67.4 +/- 9.1 m/s. This probably represents conduction velocity...

Open-Door Expansile Cervical Laminoplasty Using Titanium Miniplates: Early Clinical Experiences. The author reports early clinical experiences using a special technique for cervical open-door laminoplasty in patients with cervical spondylotic myelopathy (CSM). Between June 2007 and February 2009, 20 patients with cervical myelopathy secondary to multilevel cervical spondylosis and spinal stenos...

Myelopathy, a severe condition characterised by paraparesis, sensory deficits and sphincter dysfunction, is one of the neuropsychiatric manifestations that have been described in patients with systemic lupus erythematosus (SLE). SLE-associated myelopathy may confront clinicians with a challenging decision-making process due to the broad differential diagnosis, the lack of disease-specific findi...

Alterations in motor function in cervical myelopathy secondary to degenerative disease may be due to local effects of spinal compression or distal effects related to cortical reorganization. This prospective study characterizes differences in metabolite levels in the motor cortex, specifically N-acetylaspartate, creatine, choline, myo-inositol and glutamate plus glutamine, due to alterations in...

The preceding paper by Mirich et al. [1] describes the MR findings in four subjects with biopsy-proved necrotizing myelopathy. In the first three patients, the clinical course was characterized by progressive motor and sensory dysfunction in the lower extremities, evolving over periods ranging from 3 months to 2 years. In the fourth case, the clinical course was characterized by a Brown-Sequard...