References 1. Steers WD. 5 -Reductase activity in the prostate. Urology 2001;58:17–24. 2. Horton R, Hsieh P, Barberia J, Pages L, Cosgrove M. Atered blood androgens in elderly men with prostate hyperplasia. J Clin Endocrinol Metab 1975;41: 793–6. 3. Wright F, Poizat R, Bongini M, Doukani A, Mauvais-Jarris P. Decreased urinary 5 -androstane-3 ,17 -diol glucuronide excretion in patients with beni...

In aging men, the prostate gland becomes hyperproliferative and displays a propensity toward carcinoma. Although this hyperproliferative process has been proposed to represent an inappropriate reactivation of an embryonic differentiation program, the regulatory genes responsible for normal prostate development and function are largely undefined. Here we show that the murine Nkx3.1 homeobox gene...

Holmium laser enucleation of the prostate (HoLEP) surgery has been increasingly used in urology because its advantages for benign prostatic hyperplasia (BPH) surgical treatment recent years. But, there are insufficient data literature about true frequency incidental presence adenoma within bladder following HoLEP surgery. The case is here presented a patient who underwent 5 years previously, th...

A pure leiomyoma of the prostate is a rare benign tumor. An 82-year-old man was referred to our urology department with gross hematuria and complete urinary retention. Examination revealed a benign prostatic hyperplasia. Transrectal ultrasound showed a prostate of 125 mL. Serum PSA was 1.9 µg/L. A simple retropubic prostatectomy was performed. Histopathological examination showed a pure leiomyo...

The consumption of tomatoes and tomato products has been associated with a reduced risk of prostate cancer. We observed a decrease of 10.77% in prostate-specific antigen (PSA) levels in patients with benign prostate hyperplasia who were submitted to daily ingestion of tomato paste. This was an experimental rather than a controlled study with a sample of 43 men ranging in age from 45 to 75 years...

Annotation. The article presents a review of the literature on evolution hemostasis methods during open transbladder prostatectomy in patients with benign hyperplasia. improvement has gone from suturing prostate lodge, bladder neck and capsule to partial lodge installation Foley catheter for purpose mechanical compression lodge. Ukrainian urologists, including those Vinnytsia, are highlighted. ...

Benign prostatic hyperplasia and prostate cancer remain the most prevalent urologic health concerns affecting elderly men in their lifetime. Only 20% of benign prostatic hyperplasia and prostate cancer cases coexist in the same zone of the prostate and require a long time for initiation and progression. While the pathogenesis of both diseases is not fully understood, benign prostatic hyperplasi...

PURPOSE We conducted a safety and efficacy evaluation of intraprostatic injection of PRX302, a modified pore forming protein (proaerolysin) activated by prostate specific antigen, as a highly targeted, localized approach to treat lower urinary tract symptoms due to benign prostatic hyperplasia. MATERIALS AND METHODS A total of 92 patients with I-PSS (International Prostate Symptom Score) 15 o...

A PHASE II STUDY ASSESSING THE SAFETY AND EFFICACY OF A SINGLE TREATMENT OF 100 U, 200 U, or 300 U BOTOX® COMPARED WITH PLACEBO INJECTED INTO THE PROSTATE TO TREAT LOWER URINARY TRACT SYMPTOMS (LUTS) IN PATIENTS DUE TO BENIGN PROSTATIC HYPERPLASIA Trial ID: 191622-517-05 Coordination: CMX Research Inc. Trial design: A phase II study assessing the safety and effi cacy of a single treatment of BO...

We evaluated the correlations between BMI, fasting glucose, insulin, testosterone level, insulin resistance, and prostate size in non-diabetic benign prostatic hyperplasia (BPH) patients with normal testosterone levels. Data from 212 non-diabetic BPH patients with normal testosterone levels, who underwent transurethral resection of the prostate (TURP) due to medical treatment failure, were eval...