Objective: The objective was to study the serological prevalence of post-transfusion transmitted infections such as hepatitis C virus (HCV), hepatitis B virus (HBV), and HIV among multi-transfused thalassemic individuals of the Eastern India and the socio and financial difficulties faced by them. Methods: The study was carried out from January 2012 until December 2014 involving 1711 thalassemic...

Post-transfusion purpura is a complication of blood product transfusion in which the recipient produces antiplatelet antibodies resulting in severe thrombocytopenia. The typical patient is a multiparous woman who develops sudden severe purpura 1 week after receiving a transfusion of packed red cells or whole blood. Post-transfusion purpura should, however, be considered in any patient with thro...

β- thalassemia major is a common hemoglobinopathy in humans. in some journals, numerous studies have reported different prevalence of hepatitis c among β- thalassemia major because thalassemic patients need multiple blood transfusions and blood transfusion is a common transmission pathway for hepatitis c virus. thus this study was performed for detection of anti-hcv between β- thalassemia major...

BACKGROUND Many patients with haemophilia have developed cirrhosis or hepatocellular carcinoma due to transfusion acquired chronic viral hepatitis. AIMS To assess the long term outcome of all haemophilic patients reported to have undergone orthotopic liver transplantation. METHODS Transplant centres of patients identified by medical database search were contacted and survival data assessed ...

background& objectives: hepatitis c virus is one of the recently  discovered viruses that tend to  cause chronic liver disease. hepatitis c is one of the most common types of viral  hepatitis, cirrhosis and carcinoma of liver in hemodialysis patients. the most important risk factors of  hepatitis c in dialysis patients are blood transfusion , duration of dialysis and  kidney transplantation .to...

BACKGROUND AND PURPOSE Transfusion-transmitted virus (TTV), a recently discovered DNA virus, was first identified in patients with non-A to -G hepatitis following blood transfusion. Transmission is generally via the parenteral route but recent data suggest that TTV can also be transmitted by the fecal-oral route. METHODS This cross-sectional study was conducted in March 2005 and included 324 ...

BACKGROUND Hepatitis B and C need immediate worldwide attention as the infection rates are too high. More than 240 million people have chronic (long-term) liver infections. Every year, about 600,000 people die globally due to the acute or chronic consequences of hepatitis B and more than 350,000 people die from hepatitis C-related liver diseases. METHODS Our study was designed as a case-contr...

To study the incidence and outcome of GB virus C (GBV-C) infection in blood recipients. Serum samples collected in a prospective study were examined for GBV-C RNA by a nested polymerase chain reaction assay. Among the 400 adults who underwent cardiac surgery, 40 were positive for GBV-C RNA, including six whose pretransfusion sera were already positive and seven coinfected with hepatitis C virus...

In order to identify the risk factors for hepatitis C virus (HCV) infections, a case-control study was conducted from September 1993 to April 1994. HCV infection was confirmed by the second generation of recombinant immunoblot assay. Sixty-four cases and 128 controls matched for age and sex with a 1:2 ratio of cases to controls were enrolled. Exposure data were obtained from all participants by...