Based on the analysis of literature data and our own research, we have developed the original concept of etiology and pathogenesis of peptic ulcer disease. An analysis of the literature shows that none of the theories of pathogenesis of peptic ulcer disease does not cover the full diversity of the involved functions and their shifts, which lead to the development of ulcers in the stomach and th...

Background: Chronic inflammation and dys-regulation of the immune system mechanisms are now well established as primary triggers of gastric cancer and peptic ulcer disease. Galectin-9 (Gal-9) is a member of the galectin family and known as an inducer of cell aggregation, adhesion and apoptosis. Gal-9 interaction with its main ligand T-cell immunoglobulin and mucin domain protein-3 (Tim-3) leads...

To cite: Lobão B. BMJ Case Reports Published online: [please include Day Month Year] doi:10.1136/bcr-2012007915 DESCRIPTION A 78-year-old woman with a history of peptic ulcer and recent use of non-steroidal anti-inflammatory medication presented to the emergency department with a 3-day history of progressively worsening abdominal distention and pain. She had been seen at the same emergency depa...

Ever since herbs were used from the ancient ages to treat various diseases in one or other form of drugs for betterment mankind. Due this usage slowly verge cam e a decline over exploitation which resulted decrease production natural resources. Looking benefits flora and fauna rehabilitees tissue culture, co preservation, plantation etc. availability its form. Nature is best chemist, helps comb...

  Background and Objective: Long period risk of gastric carcinoma in people affected with chronic Helicobacter pylori gastritis is 5 times more than normal people. Perhaps histological changes due to helicobacter pylori infection could be used for screening people at risk of gastric carcinoma and peptic ulcer. Materials and Methods: This study has been carried out as a cross...

BACKGROUND The benefits of the Helicobacter pylori test-and-treat strategy are attributable largely to the cure of peptic ulcer disease while limiting the use of endoscopy. AIM To reappraise the test-and-treat strategy and empirical proton pump inhibitor therapy for the management of uninvestigated dyspepsia in the light of the decreasing prevalence of H. pylori infection, peptic ulcer diseas...

The conventional biomedical model used for medical research and disease management is a linear model in which the cause-effect relationship is important. In contrast, the model used in psychosomatic medicine is a bio-psychosocial model in which much importance is attached to interactions and relationships among various factors, as well as to the individuality of the patients. When peptic ulcer ...