BACKGROUND We wished to compare the nuisance parameters of pediatric vs. adult randomized-trials (RCTs) and determine if the latter can be used in sample size computations of the former. METHODS In this meta-epidemiologic empirical evaluation we examined meta-analyses from the Cochrane Database of Systematic-Reviews, with at least one pediatric-RCT and at least one adult-RCT. Within each meta...

IMPORTANCE Previous assessments of readiness of emergency departments (EDs) have not been comprehensive and have shown relatively poor pediatric readiness, with a reported weighted pediatric readiness score (WPRS) of 55. OBJECTIVES To assess US EDs for pediatric readiness based on compliance with the 2009 guidelines for care of children in EDs; to evaluate the effect of physician/nurse pediat...

OBJECTIVE To investigate the number and content of articles on pediatric medicine in family medicine journals. DESIGN Computerized survey in PubMed of the abstracts of all papers published between 2000 and 2002 in four family medicine journals. Abstracts were classified as research or nonresearch. Papers dealing with pediatric medicine were further categorized by main subject area. SETTING ...

abstract background: varicella is a highly contagious and dangerous disease especially in immunocompromised patients. children with cancer are at increased risk of severe illness and may fatal cases occur. vaccination from vzv ( varicella zoster vaccine) infection can be safe, immunogenic, and effective in children with leukemia who meet the criteria and are at the risk of serious disease or de...

abstract background totally implantable central venous access devices (ports) have been available for over 10 years, but have not been achieved widespread use in pediatric oncology patients. ports facilitate the administration of chemotherapy in children with cancer. materials and methods in this study, early complications of implantable central venous access devices in children with different ...

Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. Glucocorticoids (e.g., dexamethasone) form a critical component of chemotherapy regimens for pediatric ALL, and the initial response to glucocorticoid therapy is a major prognostic factor, where resistance is predictive of poor outcome. We have previously established a clinically relevant ALL xenograft model, consisting...

background: we sought to determine the clinical characteristics of pediatric esophagitis in southern iran. methods: this cross-sectional study was conducted over a 4-year period, from 2005 to 2009, in nemazee hospital, a tertiary healthcare center in shiraz, southern iran. we consecutively included all pediatric patients (< 18 years) who underwent endoscopy in our center and had pathology-co...

objective: epilepsy is a chronic neurological disorder requiring long term therapy using antiepileptic medications. reports have incriminated long term antiepileptic drugs use in deficiency of vitamin d and bone diseases in all age groups. to investigate the association between serum 25-hydroxyvitamin d levels and pediatric epilepsy in indian patients.           methods& methods: we prospective...

background: assessment is the process of systematic collection, analysis and interpretation of data to achieve the goals. the purpose of this study was to evaluate and compare the quality of educational activities of departments of nursing and midwifery faculty of hamadan university of medical sciences. methods: this cross-sectional study was done in 2009 at the faculty of nursing and midwifery...