نتایج جستجو برای: pancreatic neoplasms

تعداد نتایج: 567731  

Journal: :Diagnostic cytopathology 2009
Xin Jing Erik-Jan Wamsteker Hong Li Robert T Pu

The aim of this retrospective study is to evaluate the diagnostic yields of combining fine needle aspiration (FNA) with brushing cytology (BC) in clinical work-up of pancreatic ductal adenocarcinoma. The study included a total of 97 patients who underwent both FNA and BC along with histologic/clinical follow-up (F/U). Cytologic diagnoses were categorized as negative for neoplasm (NEG), atypical...

2014
Eliana Amato Marco dal Molin Andrea Mafficini Jun Yu Giuseppe Malleo Borislav Rusev Matteo Fassan Davide Antonello Yoshihiko Sadakari Paola Castelli Giuseppe Zamboni Anirban Maitra Roberto Salvia Ralph H Hruban Claudio Bassi Paola Capelli Rita T Lawlor Michael Goggins Aldo Scarpa

Intraductal neoplasms are important precursors to invasive pancreatic cancer and provide an opportunity to detect and treat pancreatic neoplasia before an invasive carcinoma develops. The diagnostic evaluation of these lesions is challenging, as diagnostic imaging and cytological sampling do not provide accurate information on lesion classification, the grade of dysplasia or the presence of inv...

Journal: :The American journal of surgical pathology 2016
Takashi Muraki Michelle D Reid Olca Basturk Kee-Taek Jang Gabriela Bedolla Pelin Bagci Pardeep Mittal Bahar Memis Nora Katabi Sudeshna Bandyopadhyay Juan M Sarmiento Alyssa Krasinskas David S Klimstra Volkan Adsay

Undifferentiated carcinomas with osteoclastic giant cells of the pancreas (OGC) are rare tumors. The current impression in the literature is that they are highly aggressive tumors similar in prognosis to ductal adenocarcinomas. In this study, the clinicopathologic characteristics of 38 resected OGCs were investigated and contrasted with 725 resected pancreatic ductal adenocarcinomas without ost...

Journal: :Endocrine-related cancer 2008
Thorvardur R Halfdanarson Joseph Rubin Michael B Farnell Clive S Grant Gloria M Petersen

Pancreatic endocrine tumors (PETs) are uncommon tumors with an annual incidence <1 per 100 000 person-years in the general population. The PETs that produce hormones resulting in symptoms are designated as functional. The majority of PETs are non-functional. Of the functional tumors, insulinomas are the most common, followed by gastrinomas. The clinical course of patients with PETs is variable ...

Journal: :Cirugia espanola 2015
Franz Robert Apodaca-Torrez Michelle L de Oliveira Tarcísio Triviño Alberto Goldenberg Edson José Lobo

Pancreatic endocrine neoplasms are a group of tumors that sporadically affect this gland, although their etiopathogenesis, diagnosis and treatment are still object of debate. The approximate incidence of these neoplasms is from 1 to 2% of all pancreatic tumors and their clinical symptoms depend on the production of hormones or biologically active amines. The cystic presentation of these tumors ...

2017

Pancreatic endocrine neoplasms are a group of tumors that sporadically affect this gland, although their etiopathogenesis, diagnosis and treatment are still object of debate. The approximate incidence of these neoplasms is from 1 to 2% of all pancreatic tumors and their clinical symptoms depend on the production of hormones or biologically active amines. The cystic presentation of these tumors ...

Journal: :Digestive surgery 2017
Shuji Suzuki Hideki Kajiyama Akira Takemura Jiro Shimazaki Kiyotaka Nishida Mitsugi Shimoda

BACKGROUND Total pancreatectomy (TP) is not more beneficial than less aggressive resection techniques for the treatment of pancreatic neoplasms and is associated with high morbidity and mortality. However, with advances in surgical techniques and glycemic monitoring, and the development of synthetic insulin and pancreatic enzymes for postoperative treatment, TP has been increasingly indicated. ...

Journal: :Pancreas 2014
Teppei Aso Takao Ohtsuka Koji Tamura Noboru Ideno Hiroshi Kono Yosuke Nagayoshi Kennoki Ohuchida Junji Ueda Shunnichi Takahata Koji Shindo Shinichi Aishima Yoshinao Oda Kazuhiro Mizumoto Masao Tanaka

OBJECTIVES Aberrant expression of several microRNAs (miRs) has been reported in various neoplasms including intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. MicroRNA-196a (miR-196a) is up-regulated in Barrett esophagus (characterized by intestinal metaplasia) and in colorectal cancer; this relationship between intestinal characteristics and miR-196a might also be applicable to ...

2017
Elvira Pelosi Germana Castelli Ugo Testa

Pancreatic Ductal Adenocarcinoma (PDAC) is the fourth most common cause of cancer-related death and is the most lethal of common malignancies with a five-year survival rate of <10%. PDAC arises from different types of non-invasive precursor lesions: intraductal papillary mucinous neoplasms, mucinous cystic neoplasms and pancreatic intraepithelial neoplasia. The genetic landscape of PDAC is char...

2013
Chijioke Enweluzo Simanta Dutta Fahad Aziz Stephen Lenfest

Pancreatic cancer is well known to be an aggressive and highly malignant condition with varied ways of presentation. Pancreatic cystic neoplasms are very uncommon causes of pancreatic malignancy and can often be ignored or missed, especially in the early stages. We present the case of a 49-year-old Caucasian male with no past medical history presenting to an outside facility with sudden epigast...

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