Objective: The aim of the study is to perform a computational consisting molecular docking for polyphenols subjected in silico studies identify new lead antimicrobial activity which has been reported yet or not used yet. Methods: Schrödinger Maestro 11.3 performed enzyme FabH (β-ketoacyl-acyl carrier protein synthase III) (PDB ID: 5BNR) with polyphenol. targeted compounds were docked against an...

stem cells are naïve or master cells. this means they can transform into special 200 cell types as needed by body, and each of these cells has just one function. stem cells are found in many parts of the human body, although some sources have richer concentrations than others. some excellent sources of stem cells, such as bone marrow, peripheral blood, cord blood, other tissue stem cells and hu...

recently, cell therapy has sparked a revolution in ischemic heart disease that will in the future help clinicians to cure patients. earlier investigations in animal models and clinical trials have suggested that positive paracrine effects such as neoangiogenesis and anti-apoptotic can improve myocardial function. in this regard the royan cell therapy center designed a few trials in collaboratio...

introduction:first, definition the stem cell refers to those cells that are still not clear and are not equipped for a particular task. these cells have proliferative properties and  ability to differentiate into other types of cells have become. this characteristic of stem cells to self-directed has absorbed professional opinion that extensive research is done in this regard. nowadays, stem ce...

liver failure, in an acute or chronic form, is a growing health problem ranking as one of the leading causes of death worldwide. inborn errors of metabolism characterized by defects in hepatic enzymes or other proteins with metabolic functions, such as receptors or transporters accompanied with environmental factors involve etiology and presentation of liver failure. currently, the only establi...

The present study provides an in-depth characterisation of the non-anthocyanin and anthocyanin phenolic compounds potato peels from ten coloured varieties. Furthermore, underexplored bioactive potential (antioxidant, cytotoxic anti-inflammatory capacities) studied is comprehensively analysed. Among phenolics, caffeic a caffeoylquinic acid were found in highest concentrations all samples, which ...

Five paeonol glycosides, suffruticosides A, B, C, D, and E, and a monoterpene glucoside, galloyl-oxypaeoniflorin, were isolated from the glycosidic fraction of Chinese Moutan Cortex, the root cortex of Paeonia suffruticosa Andrews, together with paeonolide, apiopaeonoside, galloyl-paeoniflorin, oxypaeoniflorin, and paeoniflorin. The structures of five suffruticosides and galloyl-oxypaeoniflorin...

abstract background: the aim of this study was to compare the effects of the second- and third-generation oral contraceptives on women’s reproductive sexual function. materials and methods: this randomized, double-blind, placebo-controlled clinical trial was conducted on 82 married women of reproductive age in tehran. samples were randomized into the groups receiving second- and third-generatio...

The repeated, independent evolution of phenotypic traits reflects adaptation to similar selective pressures. In some circumstances, parallel phenotypic evolution has a common genetic basis. Here, we investigate the types of genetic change responsible for the repeated evolution of red flowers among Ipomoea species. We identified three independent transitions from cyanidin- (blue/purple) to pelar...