Introduction: Recently, it has been demonstrated that olive leaf extract and its main component have calcium channel blocker, anti-inflammatory and anti-oxidative properties. However, the effects of olive leaf extract on opioid dependence have not yet been clarified. Methods: To develop morphine dependence, morphine was injected twice daily for 7 days according to an escalating dose in rats...

Objectives Oleuropein is the main bioactive polyphenolic compound in olive leaves, olive, and oil. Its anticancer, antioxidant, antiinflammatory effects have been proven through several vitro vivo studies. This study aimed to explore of oleuropein on cyclophosphamideand epirubicin-induced toxicity female rats. Materials Methods Seven groups containing eight rats each group were formed. Four cyc...

Background: Skin burn is one of the most common complications throughout world. Olive derivatives have been used for treatment skin lesions in Iran. Oleuropein main constituents olive leaves. Objectives: The aim present study was to evaluate healing effects oleuropein cream on second-degree burns wounds a rat model. Methods: This experimental performed 72 male Wistar rats. Superficial were indu...

This paper reports a methodology for fast analysis of two important antioxidants: tyrosol and oleuropein in real samples of alimentary oils by using a ready-to-use portable microfluidic system (MicruX ® iHVStat) based on microchips electrophoresis with electrochemical detection. The portable system integrates for the first time a high voltage power supply and a bipotentiostat for using microflu...