نتایج جستجو برای: neuropeptides

تعداد نتایج: 9355  

Journal: :Pharmacological reports : PR 2006
Barbara Zegarska Agnieszka Lelińska Tomasz Tyrakowski

The aim of this paper is to present the state of knowledge on cutaneous neurogenic inflammation. Peripheral effector functions served by afferent sensory neurons underlie the so-called neurogenic inflammation. The mechanism of cutaneous neurogenic inflammation is connected with the release of neuropeptides from the sensory endings. They also exert a number of functions within the immune system....

Journal: :Current drug targets. CNS and neurological disorders 2003
Ursula F Bailer Walter H Kaye

Neuropeptides play an important role in the regulation of feeding behavior and obesity. The mechanisms for controlling food intake involve a complicated interplay between peripheral systems (including gustatory stimulation, gastrointestinal peptide secretion, and vagal afferent nerve responses) and central nervous system (CNS) neuropeptides and/or monoamines. These neuronal systems include neur...

Journal: :Neuro endocrinology letters 2003
Isabelle Fournier Robert Day Michel Salzet

The measure of neuropeptides is an important tool in biology to better define endocrine and neuroendocrine function. Traditionally most methods have relied on the development of specific antibodies. Newer molecular methodologies have used measures of gene expression of neuropeptide precursors, such as Northern blot, PCR or in situ hybridization analysis. Matrix-assisted laser desorption/ionizat...

2015
Yan Wang Mingxia Wang Sanwen Yin Richard Jang Jian Wang Zhidong Xue Tao Xu

Neuropeptides play a variety of roles in many physiological processes and serve as potential therapeutic targets for the treatment of some nervous-system disorders. In recent years, there has been a tremendous increase in the number of identified neuropeptides. Therefore, we have developed NeuroPep, a comprehensive resource of neuropeptides, which holds 5949 non-redundant neuropeptide entries o...

Journal: :Inflammatory bowel diseases 2007
Kara J Gross Charalabos Pothoulakis

Inflammatory bowel disease (IBD) is a chronic, relapsing condition involving complex interactions between genes and the environment. The mechanisms triggering the initial attack and relapses, however, are not well understood. In the past several years the enteric nervous system (ENS) has been implicated in the pathophysiology of IBD. Both the ENS and the central nervous system (CNS) can amplify...

2017
Daniel Thiel Philipp Bauknecht Gáspár Jékely Andreas Hejnol

Animal behaviour often comprises spatially separated sub-reactions and even ciliated larvae are able to coordinate sub-reactions of complex behaviours (metamorphosis, feeding). How these sub-reactions are coordinated is currently not well understood. Neuropeptides are potential candidates for triggering larval behaviour. However, although their immunoreactivity has been widely analysed, their f...

2014
Claudia Lieberwirth Zuoxin Wang

Affiliative social relationships (e.g., among spouses, family members, and friends) play an essential role in human society. These relationships affect psychological, physiological, and behavioral functions. As positive and enduring bonds are critical for the overall well-being of humans, it is not surprising that considerable effort has been made to study the neurobiological mechanisms that un...

Journal: :Frontiers in neuroendocrinology 1996
M M Klavdieva

One of the important developments during the neuroendocrine period from 1955 to 1973 was the emergence of a new, unique research area: systematic studies of the actions of peptides on the central nervous system, including psychotropic and behavioral effects. During this period, the studies were concerned primarily with substance P, bradykinin, angiotensin,ACTH,MSH, and vasopressin. Studies on s...

Journal: :American journal of respiratory cell and molecular biology 1999
A J Cohen Y E Miller

Pulmonary neuroendocrine cells exhibit highly specialized differentiation with a neurosecretory phenotype and significant bioactive peptide hormone content. In addition to these functions, pulmonary neuroendocrine cells have been demonstrated to act as chemoreceptors for hypoxia (1). Specific pulmonary disorders, including bronchopulmonary dysplasia, bronchiectasis, cystic fibrosis, pulmonary h...

2013
Maurice R. Elphick Sufyan Achhala Natalia Martynyuk

The SALMFamides are a family of neuropeptides that act as muscle relaxants in echinoderms. Two types of SALMFamides have been identified: L-type (e.g. the starfish neuropeptides S1 and S2) with the C-terminal motif LxFamide (x is variable) and F-type with the C-terminal motif FxFamide. In the sea urchin Strongylocentrotus purpuratus (class Echinoidea) there are two SALMFamide genes, one encodin...

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