Background: Attention Deficit Hyperactivity Disorder (ADHD) is the most frequent neurobehavioral syndrome in childhood, causing significant impairment family, social and academic performance of children. A tool to help both diagnosis follow-up schoolchildren SNAP-IV scale, which evaluate 18 behaviors, according answers parents and/or teachers.

Mercury (Hg) exposure is known to damage vital components of the central nervous system primarily through oxidative stress. Although Phyllanthus amarus (PA) reported be rich in antioxidants, there a dearth relevant research evidence show its protective activity against Mercuric chloride (HgCl2)-induced neurotoxicity. Accordingly, this study was designed investigate possible aqueous leaf extract...

The ontogeny of fetal autonomic, motoric, state, and interactive functioning was investigated longitudinally in a sample of 31 healthy fetuses from 20 weeks through term. Fetal heart rate and movement data were collected during 50 min of doppler-based fetal monitoring at 6 gestational ages. Measures of fetal heart rate and variability, activity level and vigor, behavioral state, and reactivity ...

Martin Farlow MD, editor. Dr. Farlow of Indiana University School of Medicine received research grant support from BristolMyersSquibb, Danone, Eisai, Elan, Eli Lilly, Genentech, Novartis, OctaPharma, Pfizer, Roche, Sanofi-Aventis, and Sonexa; honorariums from Eisai, Forest Laboratories, Pfizer, and Novartis for speaking engagements; and fees from Accera, Alltech, Astellas, Baxter Healthcare, Ba...

Acute exposure to the organophosphate pesticide chlorpyrifos (CPF) on gestation day 12 (GD12, 200 mg/kg/ml, SC) causes extensive neurochemical changes in maternal brain but lesser changes in fetal brain. In the present study, we examined the relative neurotoxicity of repeated, lower-level CPF exposures during gestation in rats. Pregnant Sprague-Dawley rats were exposed to CPF (6.25, 12.5, or 25...