نتایج جستجو برای: nanodrop
تعداد نتایج: 165 فیلتر نتایج به سال:
Epidemiological studies implicate dietary soy isoflavones as breast cancer preventives, especially due to their anti-estrogenic properties. However, soy isoflavones may also have a role in promoting breast cancer, which has yet to be clarified. We previously reported that equol, a metabolite of the soy isoflavone daidzein, may advance breast cancer potential via upregulation of the eukaryotic i...
During hibernation in the 13-lined ground squirrel, Ictidomys tridecemlineatus, the cerebral cortex is electrically silent, yet the brainstem continues to regulate cardiorespiratory function. Previous work showed that neurons in slices through the medullary ventral respiratory column (VRC) but not the cortex, are insensitive to high doses of pentobarbital during hibernation, leading to the hypo...
Continued reduction in limited natural resources worldwide increasingly necessitates the incorporation of low-maintenance and low-input plant materials into urban landscapes. Some fine-leaved Festuca grass species have been used in formal gardens and native urban landscapes because of their inherent tolerance to abiotic stresses, but native, ornamental types (tall and non-spreading with multico...
Two projects are presented in this report. First, a silver resistant strain of Pseudomonas sp. (closest relatives Pseudomonas putida and Pseudomonas plecoglossicidaI) was isolated from Town Neck Beach in Sandwich, MA. This strain could grow in 2ppm AgNO3 and at silver nanoparticle concentrations of 2000ppm. The lack of a toxic effect of high silver nanoparticle concentrations and the formation ...
“Comparison of Topotecan Myelosupression in Differing Dosing Schedules” Nina Strollo, M.D. Mentor: Joshua Kesterson, M.D. Objective: Topotecan is a topoisomerase I inhibitor used to treat chemotherapy patients who are platinumsensitized or platinum-resistant. The selected study group had a known, limiting side effect of myelosupression. The object of this study was to compare the degree of pati...
1 Early diagnosis of drug resistant Mycobacterium tuberculosis is urgently needed to 2 optimize treatment regimens and to prevent the transmission of resistant strains. Real3 time PCR assays have been developed to detect drug resistance rapidly, but none of them 4 have been widely applied due to their complexity, high cost, or requirement for advanced 5 instruments. In this study, we developed ...
16 Replication competent poxvirus vectors with an attenuation phenotype and with high 17 immunogenic capacity of the foreign expressed antigen are being pursuit as novel 18 vaccine vectors against different pathogens. In this investigation we have examined the 19 replication and immunogenic characteristics of two vaccinia virus (VACV) mutants 20 M65 and M101. These mutants were generated after ...
word count: 196 32 Text word count: 7943 33 34 Copyright © 2012, American Society for Microbiology. All Rights Reserved. J. Virol. doi:10.1128/JVI.00714-12 JVI Accepts, published online ahead of print on 24 October 2012 on July 0, 2017 by gest http/jvi.asm .rg/ D ow nladed fom 35 ABSTRACT 36 Influenza A viruses commonly cause pancreatitis in naturally and experimentally infected 37 animals. In ...
Bartonella are hemotropic bacteria responsible for emerging zoonosis. These heme auxotroph alphaproteobacteria must import heme for their growth, since they cannot synthesize it. To import exogenous heme, Bartonella genomes encode for a complete heme uptake system enabling transportation of this compound into the cytoplasm and degrading it to release iron. In addition, these bacteria encode for...
Activation of the inositol-requiring enzyme-1 alpha (IRE1a) protein caused by endoplasmic reticulum stress results in the homodimerization of the N-terminal endoplasmic reticulum luminal domains, autophosphorylation of the cytoplasmic kinase domains, and conformational changes to the cytoplasmic endoribonuclease (RNase) domains, which render them functional and can lead to the splicing of X-box...
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