objective(s): this study was performed to investigate the effects of mucosal acidification on mrna expression and protein synthesis of cystathionine gamma lyase (cse), cystathionine beta synthase (cbs), and mucosal release of h2s in gastric mucosa in rats. materials and methods:thirty-two rats were randomly assigned into 4 groups (8 in each), including: the control group, hcl (10 mm) treated gr...

The mucosal cytokine response of healthy humans to parasitic helminths has never been reported. We investigated the systemic and mucosal cytokine responses to hookworm infection in experimentally infected, previously hookworm naive individuals from non-endemic areas. We collected both peripheral blood and duodenal biopsies to assess the systemic immune response, as well as the response at the s...

Diseases of young cattle infectious etiology are the most important problem breeding. Among these diseases, greatest economic damage is caused by diseases in calves digestive system, collectively called "neonatal diarrhea". Numerous studies carried out recent years have irrefutably proven that main role occurrence diarrhea played rota-, coronaviruses, less often viral diarrhea-mucosal disease, ...

Immune protection against infectious diseases is most effective if located at the portal of entry of the pathogen. Hence, there is an increasing demand for vaccine formulations that can induce strong protective immunity following oral, respiratory, or genital tract administration. At present, only few mucosal vaccines are found on the market, but recent technological advancements and a better u...

OBJECTIVES The purpose of this study was to assess the prevalence and distribution of oral mucosal lesions in a Turkish adult population. MATERIAL AND METHODS Five thousand consecutive patients were examined during routine dental treatment. Some of the mucosal changes were diagnosed solely by clinical examination. When clinical features were not diagnostic, a biopsy was undertaken. Chi-square...

Mucosal administration of vaccines is an important approach to the induction of appropriate immune responses to microbial and other environmental antigens in systemic sites and peripheral blood as well as in most external mucosal surfaces. The development of specific antibody- or T-cell-mediated immunologic responses and the induction of mucosally induced systemic immunologic hyporesponsiveness...